AIF Protein (AA 150-299) (His tag)
-
- 抗原 See all AIF (AIFM1) 蛋白
- AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 150-299
-
宿主
- 大鼠
-
资源
- 大肠杆菌（E. Coli）
- 标记
- This AIF protein is labelled with His tag.
- 序列
- Arg 150-Val 299
- 产品特性
- A DNA sequence encoding the Rat AIF-M1 protein (Q9JM53) (Arg 150-Val 299) was expressed with a N-His tag.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product AIFM1 蛋白
-
Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (AA 420-529) protein (GST tag)
AIFM1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (AA 98-609) protein (His tag)AIFM1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (AA 1-613) protein (GST tag)AIFM1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (Transcript Variant 4) protein (His tag)AIFM1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (AA 103-612), (partial) protein (His-SUMO Tag)AIFM1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 缓冲液
-
Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
-
- 抗原
- AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))
- 别名
- AIF-M1 (AIFM1 产品)
- 别名
- AIF Protein, CMTX4 Protein, COWCK Protein, COXPD6 Protein, PDCD8 Protein, CG7263 Protein, DmAIF Protein, Dmel\\CG7263 Protein, GB16024 Protein, DDBDRAFT_0187853 Protein, DDBDRAFT_0191137 Protein, DDB_0187853 Protein, DDB_0191137 Protein, aif Protein, pdcd8 Protein, AIFM1 Protein, PCD8 Protein, AIFsh2 Protein, Hq Protein, Pdcd8 Protein, mAIF Protein, Aif Protein, zgc:91994 Protein, apoptosis inducing factor mitochondria associated 1 Protein, allograft inflammatory factor 1 Protein, Apoptosis inducing factor Protein, apoptosis-inducing factor 1, mitochondrial Protein, apoptosis inducing factor Protein, apoptosis inducing factor, mitochondria associated 1 Protein, apoptosis-inducing factor, mitochondrion-associated, 1 Protein, apoptosis-inducing factor, mitochondrion-associated 1 Protein, AIFM1 Protein, AIF1 Protein, AIF Protein, LOC412212 Protein, aif Protein, aifm1 Protein, Aifm1 Protein
- 背景
-
Abbreviation: AIF-M1
Target Synonym: AIFM1,Apoptosis inducing factor 1,mitochondrial,Apoptosis inducing factor,CMTX4,COWCK,COXPD6,Harlequin,mitochondrial,PDCD 8,Programmed cell death 8,Striatal apoptosis inducing factor
Background: Probable oxidoreductase that has a dual role in controlling cellular life and death, during apoptosis, it is translocated from the mitochondria to the nucleus to function as a proapoptotic factor in a caspase-independent pathway, while in normal mitochondria, it functions as an antiapoptotic factor via its oxidoreductase activity. The soluble form (AIFsol) found in the nucleus induces 'parthanatos' i.e., caspase-independent fragmentation of chromosomal DNA. Interacts with EIF3G,and thereby inhibits the EIF3 machinery and protein synthesis, and activates casapse-7 to amplify apoptosis. Plays a critical role in caspase-independent, pyknotic cell death in hydrogen peroxide-exposed cells. Binds to DNA in a sequence-independent manner.
- 分子量
-
Calculated MW: 16.39 kDa
Observed MW: 18 kDa
- UniProt
- Q9JM53
- 途径
- Apoptosis, Positive Regulation of Endopeptidase Activity, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Warburg Effect
-
