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EZH1 Protein (AA 201-400) (His tag)

EZH1 宿主: 大鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7505524
发货至: 中国
  • 抗原 See all EZH1 蛋白
    EZH1 (Enhancer of Zeste Homolog 1 (EZH1))
    蛋白类型
    Recombinant
    产品特性
    AA 201-400
    宿主
    • 3
    • 3
    大鼠
    资源
    • 3
    • 2
    • 1
    大肠杆菌(E. Coli)
    标记
    This EZH1 protein is labelled with His tag.
    序列
    Lys 201-Ser 400
    产品特性
    A DNA sequence encoding the Rat EEZH1 protein (F1LZH3) (Lys 201-Ser 400) was expressed with a N-His tag.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    12 months
  • 抗原
    EZH1 (Enhancer of Zeste Homolog 1 (EZH1))
    别名
    EZH1 (EZH1 产品)
    别名
    KMT6B Protein, si:ch211-250i3.1 Protein, zgc:136829 Protein, AW557915 Protein, mKIAA0388 Protein, EZH1 Protein, enhancer of zeste 1 polycomb repressive complex 2 subunit Protein, EZH1 Protein, ezh1 Protein, Ezh1 Protein
    背景

    Abbreviation: EZH1

    Target Synonym: Enhancer of zeste homolog 1,ENX2,Histone-lysine N-methyltransferase EZH1

    Background: Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH1-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.

    分子量

    Calculated MW: 21.89 kDa

    Observed MW: 28 kDa

    UniProt
    F1LZH3
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