S100A12 Protein (AA 2-92) (His tag)
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- 抗原 See all S100A12 蛋白
- S100A12 (S100 Calcium Binding Protein A12 (S100A12))
- 蛋白类型
- Recombinant
- 产品特性
- AA 2-92
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宿主
- Pig
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资源
- 大肠杆菌(E. Coli)
- 标记
- This S100A12 protein is labelled with His tag.
- 序列
- Thr 2-Glu 92
- 产品特性
- A DNA sequence encoding the Pig S100A12 protein (P80310) (Thr 2-Glu 92) was expressed with N-His tag.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product S100A12 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- S100A12 (S100 Calcium Binding Protein A12 (S100A12))
- 别名
- S100A12 (S100A12 产品)
- 别名
- CAAF1 Protein, CAGC Protein, CGRP Protein, ENRAGE Protein, MRP-6 Protein, MRP6 Protein, p6 Protein, CO-AG Protein, EN-RAGE Protein, S100 calcium binding protein A12 Protein, protein S100-A12 Protein, S100A12 Protein, LOC101103771 Protein
- 背景
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Abbreviation: S100A12
Target Synonym: Protein S100-A12,Calcium-binding protein in amniotic fluid 1,Calgranulin-C,Extracellular newly identified RAGE-binding protein,Migration inhibitory factor-related protein 6,S100 calcium-binding protein A12,Calcitermin,S100A12,CGRP,MRP-6,EN-RAGE
Background: S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100 % soluble in ammonium sulfate at neutral pH . Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of intracellular and extracellular functions. They are involved in regulation of protein phosphorylation, transcription factors, the dynamics of cytoskeleton constituents, enzyme activities, cell growth and differentiation, and the inflammatory response. Protein S100-A12, also known as S100 calcium-binding protein A12, Calcium-binding protein in amniotic fluid 1, Calgranulin-C, and S100A12, is a member of the S-101 family. Like the majority of S100 proteins, S100A12 is a dimer, with the interface between the two subunits being composed mostly of hydrophobic residues. The fold of S100A12 is similar to the other known crystal and solution structures of S100 proteins, except for the linker region between the two EF-hand motifs. S100A12 plays an important role in the inflammatory response.
- 分子量
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Calculated MW: 9.9 kDa
Observed MW: 12 kDa
- UniProt
- P80310
- 途径
- Toll-Like Receptors Cascades, S100 Proteins
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