L-Selectin Protein (AA 39-332) (His tag)
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- 抗原 See all L-Selectin (SELL) 蛋白
- L-Selectin (SELL) (Selectin L (SELL))
- 蛋白类型
- Recombinant
- 产品特性
- AA 39-332
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宿主
- 小鼠
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资源
- 大肠杆菌（E. Coli）
- 标记
- This L-Selectin protein is labelled with His tag.
- 序列
- Trp 39-Asn 332
- 产品特性
- A DNA sequence encoding the Mouse CD62L/L-Selectin protein (P18337) (Trp 39-Asn 332) was expressed with N-His tag.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product SELL 蛋白
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Selectin L (SELL) (AA 39-332) protein (His tag)
SELL 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Selectin L (SELL) (AA 39-332) protein (His tag)SELL 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Selectin L (SELL) (AA 190-332) protein (His tag)SELL 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Selectin L (SELL) (AA 29-332) protein (His tag)SELL 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Selectin L (SELL) (AA 1-375) protein (GST tag)SELL 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Selectin L (SELL) (Active) protein (His tag,Fc Tag)SELL 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- L-Selectin (SELL) (Selectin L (SELL))
- 别名
- CD62L (SELL 产品)
- 别名
- CD62L Protein, LAM1 Protein, LECAM1 Protein, LEU8 Protein, LNHR Protein, LSEL Protein, LYAM1 Protein, PLNHR Protein, TQ1 Protein, A.11 Protein, L-selectin Protein, LECAM-1 Protein, SELE Protein, AI528707 Protein, Lnhr Protein, Ly-22 Protein, Ly-m22 Protein, Lyam-1 Protein, Lyam1 Protein, selectin L Protein, selectin, lymphocyte Protein, SELL Protein, Sell Protein
- 背景
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Abbreviation: CD62L;L-Selectin
Target Synonym: L-selectin;Sell;CD62 antigen-like family member L;Leukocyte adhesion molecule 1;LECAM1;Lymph node homing receptor;Lymphocyte antigen 22;CD62L;LECAM-1;Lnhr;Ly-22;Ly-m22;Lyam-1;Lyam1
Background: L-selectin (SELL), also known as CD62L, is a key adhesion molecule that regulates both the migration of leukocytes at sites of inflammation and the recirculation of lymphocytes between blood and lymphoid tissues. It belongs to the selectin family of proteins, and consisting of a large, highly glycosylated, extracellular domain, a single spanning transmembrane domain and a small cytoplasmic tail. L-selectin is the only selectin expressed on leukocytes and mediates a number of leukocyte-endothelial interactions. L-selectin acts as a "homing receptor" for leukocytes to enter secondary lymphoid tissues via high endothelial venules. Ligands present on endothelial cells will bind to leukocyte expressing L-selectin, slowing leukocyte trafficking through the blood, and facilitating entry into a secondary lymphoid organ at that point. L-selectin-mediated lymphocyte recirculation is required for maintaining the appropriate tissue distribution of lymphocyte subpopulations including naïve and effector subsets such as regulatory T cells. In addition, L-selectin-mediated entry into peripheral lymph nodes is required for optimal induction of lymphocyte homeostatic proliferation during lymphopenia. Importantly, L-selectin has been shown to have both adhesive and signaling functions during leukocyte migration. L-selectin has also been shown to mediate leukocyte recruitment during chronic inflammatory and autoimmune diseases and thus is a potential therapeutic target for drug development.
- 分子量
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Calculated MW: 32.23 kDa
Observed MW: 41 kDa
- UniProt
- P18337
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