FGA Protein (AA 434-789) (His tag)
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- 抗原 See all FGA 蛋白
- FGA (Fibrinogen alpha Chain (FGA))
- 蛋白类型
- Recombinant
- 产品特性
- AA 434-789
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宿主
- 小鼠
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资源
- 大肠杆菌(E. Coli)
- 标记
- This FGA protein is labelled with His tag.
- 序列
- Asp 434-Gln 789
- 产品特性
- A DNA sequence encoding the Mouse FGA protein (E9PV24 ) (Asp 434-Gln 789) was expressed with N-His tag.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product FGA 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- FGA (Fibrinogen alpha Chain (FGA))
- 别名
- FGA (FGA 产品)
- 别名
- Fib2 Protein, ENSMUSG00000059807 Protein, Fib Protein, Ac1873 Protein, Fba5e Protein, fibrinogen alpha chain Protein, FGA Protein, Fga Protein, LOC698244 Protein
- 背景
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Abbreviation: FGA,Fibrinogen A
Target Synonym: FGA,Fib2,Fibrinogen A,Fibrinogen alpha chain,Fibrinogen Type I,fibrinogen,A alpha polypeptide,FPA
Background: Fibrinogen is a 340 kDa, secreted glycoprotein complex that is found in blood at concentrations of 150-400 mg/dL. It is secreted primarily by hepatocytes, but is also reported to be expressed by fibroblasts, type I alveolar epithelium, intestinal epithelium and some tumor cells. Fibrinogen is a homodimer that is composed of two, three-polypeptide chain subunits. Fibrinogen plays a central role in clot formation. Conversion of fibrinogen to fibrin is triggered by thrombin, which cleaves fibrinopeptides A and B from alpha and beta chains, and thus exposes the N-terminal polymerization sites responsible for the formation of the soft clot. The soft clot is converted into the hard clot by factor XIIIA which catalyzes the epsilon-(gamma-glutamyl)lysine cross-linking between gamma chains (stronger) and between alpha chains (weaker) of different monomers. Fibrinogen is also a component of the ECM and binds to cell surface molecules on inflammatory cells. Mature mouse alpha, beta and gamma -chains share 67 % , 85 % and 83 % aa identity with human alpha, beta and gamma -chains, respectively.
- 分子量
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Calculated MW: 39.05 kDa
Observed MW: 50 kDa
- UniProt
- E9PV24
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