MME Protein (AA 461-750) (His tag)
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- 抗原 See all MME 蛋白
- MME (Membrane Metallo-Endopeptidase (MME))
- 蛋白类型
- Recombinant
- 产品特性
- AA 461-750
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宿主
- 小鼠
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资源
- 大肠杆菌(E. Coli)
- 标记
- This MME protein is labelled with His tag.
- 序列
- Met 461-Trp 750
- 产品特性
- A DNA sequence encoding the Mouse MME protein (Q61391) (Met 461-Trp 750) was expressed with N-His tag.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product MME 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- MME (Membrane Metallo-Endopeptidase (MME))
- 别名
- MME (MME 产品)
- 别名
- CALLA Protein, CD10 Protein, NEP Protein, SFE Protein, 6030454K05Rik Protein, C85356 Protein, Nep Protein, neprilysin Protein, membrane metalloendopeptidase Protein, membrane metallo endopeptidase Protein, membrane metallo-endopeptidase Protein, MME Protein, Mme Protein
- 背景
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Abbreviation: MME,CD10,Neprilysin
Target Synonym: Atriopeptidase,CALLA,Enkephalinase,EPN,NEP,Neprilysin,neprilysin-390,neprilysin-411,SFE,Skin fibroblast elastase
Background: CD10, also known as neprilysin, common acute lymphoblastic leukemia antigen (CALLA), or neutral endopeptidase (NEP), is a zinc-dependent transmembrane metallo-endopeptidase. CD10 cleaves peptides at the N-terminal side of hydrophobic amino acid residues and deactivates a variety of signaling peptides. CD10 was shown to be one of the markers for a natural killer cell-restricted progenitor in fetal and adult tissues. Studies also suggest CD10 as a phenotypic marker to distinguish mature neutrophils from immature neutrophils in patients with inflammation. In addition, CD10+GPR77+ carcinoma-associated fibroblasts (CAFs) promote tumor formation and chemoresistance.
- 分子量
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Calculated MW: 31.79 kDa
Observed MW: 32 kDa
- UniProt
- Q61391
- 途径
- RTK signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
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