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MME Protein (AA 461-750) (His tag)

MME 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7505418
发货至: 中国
  • 抗原 See all MME 蛋白
    MME (Membrane Metallo-Endopeptidase (MME))
    蛋白类型
    Recombinant
    产品特性
    AA 461-750
    宿主
    • 15
    • 5
    • 4
    • 1
    小鼠
    资源
    • 11
    • 6
    • 3
    • 2
    • 1
    大肠杆菌(E. Coli)
    标记
    This MME protein is labelled with His tag.
    序列
    Met 461-Trp 750
    产品特性
    A DNA sequence encoding the Mouse MME protein (Q61391) (Met 461-Trp 750) was expressed with N-His tag.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product MME 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    12 months
  • 抗原
    MME (Membrane Metallo-Endopeptidase (MME))
    别名
    MME (MME 产品)
    别名
    CALLA Protein, CD10 Protein, NEP Protein, SFE Protein, 6030454K05Rik Protein, C85356 Protein, Nep Protein, neprilysin Protein, membrane metalloendopeptidase Protein, membrane metallo endopeptidase Protein, membrane metallo-endopeptidase Protein, MME Protein, Mme Protein
    背景

    Abbreviation: MME,CD10,Neprilysin

    Target Synonym: Atriopeptidase,CALLA,Enkephalinase,EPN,NEP,Neprilysin,neprilysin-390,neprilysin-411,SFE,Skin fibroblast elastase

    Background: CD10, also known as neprilysin, common acute lymphoblastic leukemia antigen (CALLA), or neutral endopeptidase (NEP), is a zinc-dependent transmembrane metallo-endopeptidase. CD10 cleaves peptides at the N-terminal side of hydrophobic amino acid residues and deactivates a variety of signaling peptides. CD10 was shown to be one of the markers for a natural killer cell-restricted progenitor in fetal and adult tissues. Studies also suggest CD10 as a phenotypic marker to distinguish mature neutrophils from immature neutrophils in patients with inflammation. In addition, CD10+GPR77+ carcinoma-associated fibroblasts (CAFs) promote tumor formation and chemoresistance.

    分子量

    Calculated MW: 31.79 kDa

    Observed MW: 32 kDa

    UniProt
    Q61391
    途径
    RTK signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
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