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IL-33 Protein (AA 109-266) (His tag)

IL33 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7505401
发货至: 中国
  • 抗原 See all IL-33 (IL33) 蛋白
    IL-33 (IL33) (Interleukin 33 (IL33))
    蛋白类型
    Recombinant
    产品特性
    AA 109-266
    宿主
    • 19
    • 13
    • 3
    • 2
    • 1
    • 1
    • 1
    小鼠
    资源
    • 24
    • 8
    • 2
    • 2
    • 1
    大肠杆菌(E. Coli)
    标记
    This IL-33 protein is labelled with His tag.
    序列
    Ser 109-Ile 266
    产品特性
    A DNA sequence encoding the Mouse IL-33 protein (Q8BVZ5) (Ser 109-Ile 266) was expressed with a N-His tag.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product IL33 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    12 months
  • 抗原
    IL-33 (IL33) (Interleukin 33 (IL33))
    别名
    IL-33 (IL33 产品)
    别名
    IL33 Protein, C9orf26 Protein, DVS27 Protein, IL1F11 Protein, NF-HEV Protein, NFEHEV Protein, RP11-575C20.2 Protein, 9230117N10Rik Protein, Il-33 Protein, Il1f11 Protein, RGD1311155 Protein, interleukin 33 Protein, IL33 Protein, Il33 Protein
    背景

    Abbreviation: IL-33

    Target Synonym: Interleukin 33,IL-33,IL33,C9orf26,NKHEV,Interleukin-1 family member 11,DVS27,NF-HEV and IL- 1F11

    Background: Mouse Interleukin 33 (IL-33) is a 30 kDa proinflammatory cytokine which may also regulates gene transcription in producer cells. IL-33 is constitutively expressed in smooth muscle and airway epithelia. IL-33 was identified based on sequence and structural homology with IL-1 family cytokines. It is up-regulated in arterial smooth muscle, dermal fibroblasts, and keratinocytes following IL-1 alpha or IL-1 beta stimulation. IL-33 is structurally related to IL-1, which induces helper T cells to produce type 2 cytokines and acts through the receptor IL1RL-1. BindingIL-33 to this receptor activates NF-kappa-B and MAP kinases and induces in vitro Th2 cells to produce cytokines. In vivo, IL-33 induces the expression of IL-4, IL-5, IL-13 and also leads to severe pathological changes in mucosal organs.

    分子量

    Calculated MW: 17.27 kDa

    Observed MW: 28 kDa

    UniProt
    Q8BVZ5
    途径
    Production of Molecular Mediator of Immune Response
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