IL-33 Protein (AA 109-266) (His tag)
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- 抗原 See all IL-33 (IL33) 蛋白
- IL-33 (IL33) (Interleukin 33 (IL33))
- 蛋白类型
- Recombinant
- 产品特性
- AA 109-266
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宿主
- 小鼠
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资源
- 大肠杆菌(E. Coli)
- 标记
- This IL-33 protein is labelled with His tag.
- 序列
- Ser 109-Ile 266
- 产品特性
- A DNA sequence encoding the Mouse IL-33 protein (Q8BVZ5) (Ser 109-Ile 266) was expressed with a N-His tag.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product IL33 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- IL-33 (IL33) (Interleukin 33 (IL33))
- 别名
- IL-33 (IL33 产品)
- 别名
- IL33 Protein, C9orf26 Protein, DVS27 Protein, IL1F11 Protein, NF-HEV Protein, NFEHEV Protein, RP11-575C20.2 Protein, 9230117N10Rik Protein, Il-33 Protein, Il1f11 Protein, RGD1311155 Protein, interleukin 33 Protein, IL33 Protein, Il33 Protein
- 背景
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Abbreviation: IL-33
Target Synonym: Interleukin 33,IL-33,IL33,C9orf26,NKHEV,Interleukin-1 family member 11,DVS27,NF-HEV and IL- 1F11
Background: Mouse Interleukin 33 (IL-33) is a 30 kDa proinflammatory cytokine which may also regulates gene transcription in producer cells. IL-33 is constitutively expressed in smooth muscle and airway epithelia. IL-33 was identified based on sequence and structural homology with IL-1 family cytokines. It is up-regulated in arterial smooth muscle, dermal fibroblasts, and keratinocytes following IL-1 alpha or IL-1 beta stimulation. IL-33 is structurally related to IL-1, which induces helper T cells to produce type 2 cytokines and acts through the receptor IL1RL-1. BindingIL-33 to this receptor activates NF-kappa-B and MAP kinases and induces in vitro Th2 cells to produce cytokines. In vivo, IL-33 induces the expression of IL-4, IL-5, IL-13 and also leads to severe pathological changes in mucosal organs.
- 分子量
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Calculated MW: 17.27 kDa
Observed MW: 28 kDa
- UniProt
- Q8BVZ5
- 途径
- Production of Molecular Mediator of Immune Response
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