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FABP5 Protein (AA 2-135) (His tag)

FABP5 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7505390
发货至: 中国
  • 抗原 See all FABP5 蛋白
    FABP5 (Fatty Acid Binding Protein 5 (Psoriasis-Associated) (FABP5))
    蛋白类型
    Recombinant
    产品特性
    AA 2-135
    宿主
    • 7
    • 3
    • 2
    • 1
    • 1
    小鼠
    资源
    • 8
    • 2
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This FABP5 protein is labelled with His tag.
    序列
    Ala 2-Gln 135
    产品特性
    A DNA sequence encoding the Mouse FABP5 protein (Q05816) (Ala2-Gln135) was expressed with a N-His .
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product FABP5 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    12 months
  • 抗原
    FABP5 (Fatty Acid Binding Protein 5 (Psoriasis-Associated) (FABP5))
    别名
    FABP5 (FABP5 产品)
    别名
    E-FABP Protein, EFABP Protein, KFABP Protein, PA-FABP Protein, PAFABP Protein, FABP5 Protein, Fabpe Protein, Klbp Protein, mal1 Protein, C-FABP Protein, DA11 Protein, FABP5L1 Protein, fatty acid binding protein 5 Protein, fatty acid binding protein 5, epidermal Protein, fatty acid binding protein 5 (psoriasis-associated) Protein, fatty acid binding protein 5 pseudogene 1 Protein, cationic amino acid transporter 3 pseudogene Protein, FABP5 Protein, Fabp5 Protein, FABP5P1 Protein, LOC609554 Protein
    背景

    Abbreviation: FABP5

    Target Synonym: Fatty acid-binding protein 5,Epidermal-type fatty acid-binding protein,E-FABP,Fatty acid-binding protein,epidermal,Keratinocyte lipid-binding protein,Psoriasis-associated fatty acid-binding protein homolog,PA-FABP

    Background: Fatty acid binding proteins (FABP) are small cytoplasmic lipid binding proteins that are expressed in a tissue specific manner and are involved in intracellular lipid transport. All FABPs bind free fatty acids, cholesterol, and retinoids, which differ in their selectivity, affinity and binding mechanism. Circulating FABP levels are used as indicators of tissue damage. Some FABP polymorphisms have been associated with disorders of lipid metabolism and the development of atherosclerosis. FABPs are structurally conserved, consisting of a water-filled, ligand-binding pocket surrounded by ten anti-parallel beta-barrel structures, capped by an N-terminal helix-turn-helix motif. The helical N-terminus is involved in the regulation of FA transfer from membranes. FABP5, also known as epidermal fatty acid binding protein (E-FABP), is highly expressed in epidermal cells, but also in a plethora of other tissues, including mammary gland, brain, liver, kidney, lung, adipocytes, macrophages, tongue and testis. It is associated with keratinocytes and adipocytes and is suggested to promote fatty acid availability to enzymes, protect cell structures from fatty acid attack, and target fatty acids to nuclear transcription factors. The amino acid sequence of human FABP5 is 80 % , 81 % and 92 % identical to that of mouse, rat and bovine FABP5, respectively.

    分子量

    Calculated MW: 14.63 kDa

    Observed MW: 16 kDa

    UniProt
    Q05816
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