Ceruloplasmin Protein (AA 729-1061) (His tag)
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- 抗原 See all Ceruloplasmin (CP) 蛋白
- Ceruloplasmin (CP) (Ceruloplasmin (Ferroxidase) (CP))
- 蛋白类型
- Recombinant
- 产品特性
- AA 729-1061
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宿主
- 小鼠
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资源
- 大肠杆菌（E. Coli）
- 标记
- This Ceruloplasmin protein is labelled with His tag.
- 序列
- Tyr729-Gly1061
- 产品特性
- A DNA sequence encoding the Mouse CP protein (Q61147) (Tyr729-Gly1061) was expressed with a N-His .
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product CP 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- Ceruloplasmin (CP) (Ceruloplasmin (Ferroxidase) (CP))
- 别名
- Ceruloplasmin (CP 产品)
- 别名
- CP-2 Protein, fi23f10 Protein, wu:fi23f10 Protein, D3Ertd555e Protein, CERP Protein, CP Protein, ceruloplasmin Protein, CP Protein, cp Protein, Cp Protein, LOC100533122 Protein
- 背景
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Abbreviation: Ceruloplasmin,CP
Target Synonym: CERU_MOUSE,EC:1.16.3.1,Ferroxidase
Background: Ceruloplasmin is a blue, copper-binding (6-7 atoms per molecule) glycoprotein. It has ferroxidase activity oxidizing Fe2+ to Fe3+ without releasing radical oxygen species. It is involved in iron transport across the cell membrane. Provides Cu2+ ions for the ascorbate-mediated deaminase degradation of the heparan sulfate chains of GPC1. May also play a role in fetal lung development or pulmonary antioxidant defense. Defects in CP are the cause of aceruloplasminemia (ACERULOP) [MIM:604290]. It is an autosomal recessive disorder of iron metabolism characterized by iron accumulation in the brain as well as visceral organs. Clinical features consist of the triad of retinal degeneration, diabetes mellitus and neurological disturbances. Note=Ceruloplasmin levels are decreased in Wilson disease, in which copper cannot be incorporated into ceruloplasmin in liver because of defects in the copper-transporting ATPase 2.
- 分子量
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Calculated MW: 36.52 kDa
Observed MW: 40 kDa
- UniProt
- Q61147
- 途径
- Transition Metal Ion Homeostasis
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