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AMH Protein (AA 447-554) (TRX tag,His tag)

AMH 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7505379
发货至: 中国
  • 抗原 See all AMH 蛋白
    AMH (Anti-Mullerian Hormone (AMH))
    蛋白类型
    Recombinant
    产品特性
    AA 447-554
    宿主
    • 10
    • 3
    • 2
    • 2
    • 2
    • 2
    小鼠
    资源
    • 16
    • 2
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This AMH protein is labelled with TRX tag,His tag.
    序列
    Ser447-Val554
    产品特性
    A DNA sequence encoding the Mouse AMH protein (P27106) (Ser447-Val554) was expressed with a N teriminal TRX-His tag.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product AMH 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    12 months
  • 抗原
    AMH (Anti-Mullerian Hormone (AMH))
    别名
    AMH (AMH 产品)
    别名
    AMH Protein, amh Protein, MIF Protein, MIS Protein, anti-Mullerian hormone Protein, amh Protein, AMH Protein, Amh Protein
    背景

    Abbreviation: AMH

    Target Synonym: Anti-Muellerian hormone,Muellerian-inhibiting substance,Muellerian-inhibiting factor,Amh

    Background: Anti-Mullerian hormone (AMH), a member of the TGF-beta superfamily, is produced by granulosa cells (GCs) of preantral and small antral follicles and plays a role in regulating the recruitment of primordial follicles and the FSH-dependent development of follicles. BMP15 up-regulates the transcription of AMH and that the inhibition of p38 MAPK decreases the BMP15-induced expression of AMH and SOX9, suggesting that BMP15 up-regulates the expression of AMH via the p38 MAPK signaling pathway, and this process involves the SOX9 transcription factor. AMH is widely used for assessing ovarian reserve, and it is particularly convenient, because it is thought to have minimal variability throughout the menstrual cycle. Fetal anti-Mullerian hormone (AMH) is responsible for normal male sexual differentiation, and circulating AMH is used as a marker of testicular tissue in newborns with disorders of sex development. Anti-Mullerian hormone (AMH) produced in the developing testis induces the regression of the Mullerian duct, which develops into the oviducts, uterus and upper vagina. As well as other hormone receptors, and a decreased ovarian cortex cell proliferation. These results help understand the inhibitory effects of AMH on follicular development.

    分子量

    Calculated MW: 31.77 kDa

    Observed MW: 35 kDa

    UniProt
    P27106
    途径
    Negative Regulation of Hormone Secretion
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