Cadherin 5 Protein (CDH5) (AA 25-599) (His tag)
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- 抗原 See all Cadherin 5 (CDH5) 蛋白
- Cadherin 5 (CDH5)
- 蛋白类型
- Recombinant
- 产品特性
- AA 25-599
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宿主
- 小鼠
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资源
- 大肠杆菌（E. Coli）
- 标记
- This Cadherin 5 protein is labelled with His tag.
- 序列
- Gly 25-Gln 599
- 产品特性
- A DNA sequence encoding the Mouse Cdh5 protein (P55284) (Gly 25-Gln 599) was expressed with a N-His tag.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product CDH5 蛋白
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Cadherin 5 (CDH5) (AA 51-150) protein (GST tag)
CDH5 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Cadherin 5 (CDH5) protein (His tag)CDH5 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
Cadherin 5 (CDH5) (AA 29-599) protein (hIgG-His-tag)CDH5 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 90 % by SDS - PAGE SDS
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- Cadherin 5 (CDH5)
- 别名
- Cdh5 (CDH5 产品)
- 别名
- 7B4 Protein, AA408225 Protein, Cd144 Protein, VE-Cad Protein, VECD Protein, VEcad Protein, Vec Protein, wu:fc88a07 Protein, CD144 Protein, cadherin-5 Protein, cadherin 5 Protein, CDH5 Protein, Cdh5 Protein, cdh5 Protein
- 背景
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Abbreviation: Cdh5
Target Synonym: 7B4,AA408225,Cd144,VE-Cad,Vec,VEcad,VECD,Cdh5
Background: Cadherins (Calcium dependent adhesion molecules) are a class of transmembrane proteins. Cadherin-5, also known as VE-cadherin, CDH5 and CD144, an endothelial specific cell-cell adhesion molecule, plays a pivotal role in the formation, maturation and remodeling of the vascular wall. VE-Cadherin is widely considered to be specific for vascular endothelia in which it is either the sole or the predominant cadherin, often co-existing with N-cadherin. This specificity of VE-cadherin for vascular endothelial cells is important not only in blood and lymph vessel biology and medicine, but also for cell-type-based diagnoses, notably those of metastatic tumors. As a classical cadherin, VE-Cadherin links endothelial cells together by homophilic interactions mediated by its extracellular part and associates intracellularly with the actin cytoskeleton via catenins. Mechanisms that regulate VE-cadherin-mediated adhesion are important for the control of vascular permeability and leukocyte extravasation. In addition to its adhesive functions, VE-Cadherin regulates various cellular processes such as cell proliferation and apoptosis and modulates vascular endothelial growth factor receptor functions. Consequently, VE-cadherin is essential during embryonic angiogenesis.
- 分子量
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Calculated MW: 63.14 kDa
Observed MW: 65 kDa
- UniProt
- P55284
- 途径
- Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2
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