FAP Protein (AA 26-349) (His tag)
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- 抗原 See all FAP 蛋白
- FAP (Fibroblast Activation Protein, alpha (FAP))
- 蛋白类型
- Recombinant
- 产品特性
- AA 26-349
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宿主
- 小鼠
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资源
- 大肠杆菌(E. Coli)
- 标记
- This FAP protein is labelled with His tag.
- 应用范围
- Immunogen (Imm)
- 序列
- Leu26-Gly349
- 产品特性
- A DNA sequence encoding the Mouse FAP protein (P97321) (26L-349G) was expressed with a polyhistidine tag at the N-terminus.
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product FAP 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- FAP (Fibroblast Activation Protein, alpha (FAP))
- 别名
- FAP (FAP 产品)
- 别名
- fap-A Protein, gene 13 Protein, FAP Protein, fapa Protein, dppiv Protein, seprase Protein, DPPIV Protein, FAPA Protein, fibroblast activation protein Protein, fibroblast activation protein alpha L homeolog Protein, fibroblast activation protein alpha Protein, fibroblast activation protein, alpha Protein, prolyl endopeptidase FAP Protein, Fap Protein, fap.L Protein, FAP Protein, fap Protein, LOC100547273 Protein
- 背景
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Abbreviation: FAP
Target Synonym: 170 kDa melanoma membrane bound gelatinase,170 kDa melanoma membrane-bound gelatinase,DPPIV,FAP,FAPA,Fibroblast activation protein alpha,Integral membrane serine protease,SEPR,Seprase,FAPalpha,SIMP
Background: Cell surface glycoprotein serine protease that participates in extracellular matrix degradation and involved in many cellular processes including tissue remodeling, fibrosis, wound healing, inflammation and tumor growth. Both plasma membrane and soluble forms exhibit post-proline cleaving endopeptidase activity, with a marked preference for Ala/Ser-Gly-Pro-Ser/Asn/Ala consensus sequences, on substrate such as alpha-2-antiplasmin SERPINF2 and SPRY2. Degrade also gelatin, heat-denatured type I collagen, but not native collagen type I and IV, vibronectin, tenascin, laminin, fibronectin, fibrin or casein. Have also dipeptidyl peptidase activity, exhibiting the ability to hydrolyze the prolyl bond two residues from the N-terminus of synthetic dipeptide substrates provided that the penultimate residue is proline, with a preference for Ala-Pro, Ile-Pro, Gly-Pro, Arg-Pro and Pro-Pro. Natural neuropeptide hormones for dipeptidyl peptidase are the neuropeptide Y (NPY), peptide YY (PYY), substance P (TAC1) and brain natriuretic peptide 32 (NPPB).
- 分子量
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Calculated MW: 38 kDa
Observed MW: 35-40 kDa
- UniProt
- P97321
- 途径
- Tube Formation
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