PPM1A Protein (AA 2-382) (His tag)
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- 抗原 See all PPM1A 蛋白
- PPM1A (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A))
- 蛋白类型
- Recombinant
- 产品特性
- AA 2-382
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This PPM1A protein is labelled with His tag.
- 序列
- Gly2-Trp382
- 产品特性
- A DNA sequence encoding the Human PPM1A protein (P35813) (Gly 2-Trp 382) was expressed with a N-His.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product PPM1A 蛋白
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Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) (AA 1-382) protein (GST tag)
PPM1A 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) protein (His tag)PPM1A 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 98 % as determined by SDS-PAGE
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) (Transcript Variant 1) protein (His tag)PPM1A 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)PPM1A 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- PPM1A (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A))
- 别名
- PPM1A (PPM1A 产品)
- 别名
- PP2C-ALPHA Protein, PP2CA Protein, PP2Calpha Protein, pp2ca1 Protein, ppp1r13b Protein, si:ch211-253p18.1 Protein, wu:fd42g12 Protein, zgc:153820 Protein, 2310003C21Rik Protein, 2900017D14Rik Protein, AI427932 Protein, AU017636 Protein, MMPa-2 Protein, MPPa-1 Protein, Pp2c1 Protein, pp2c-alpha Protein, pp2ca Protein, pp2calpha Protein, pp2ca2 Protein, protein phosphatase, Mg2+/Mn2+ dependent 1A Protein, protein phosphatase, Mg2+/Mn2+ dependent, 1Ab Protein, protein phosphatase 1A, magnesium dependent, alpha isoform Protein, protein phosphatase, Mg2+/Mn2+ dependent, 1A Protein, protein phosphatase, Mg2+/Mn2+ dependent 1A L homeolog Protein, protein phosphatase, Mg2+/Mn2+ dependent, 1Aa Protein, PPM1A Protein, ppm1ab Protein, Ppm1a Protein, ppm1a.L Protein, ppm1aa Protein
- 背景
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Abbreviation: PPM1A
Target Synonym: Protein Phosphatase 1A,Protein Phosphatase 2C Isoform Alpha,PP2C-Alpha,Protein Phosphatase IA,PPM1A,PPPM1A,PP2C-ALPHA,PP2CA,PP2Calpha
Background: Protein Phosphatase 1A (PPM1A) is a member of the PP2C family of Ser/Thr protein phosphatases which are known to be negative regulators of cell stress response pathways. PPM1A has a broad specificity. PPM1A negatively regulates the activities of MAP kinases and MAP kinase kinases. Also, it negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling. In addition, PPM1A can dephosphorylate cyclin-dependent kinases, and thus may be involved in cell cycle control.
- 分子量
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Calculated MW: 41.8 kDa
Observed MW: 45 kDa
- UniProt
- P35813
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