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E2F2 Protein (AA 65-437) (His tag)

E2F2 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7505314
发货至: 中国
  • 抗原 See all E2F2 蛋白
    E2F2 (E2F Transcription Factor 2 (E2F2))
    蛋白类型
    Recombinant
    产品特性
    AA 65-437
    宿主
    • 5
    • 2
    • 1
    资源
    • 2
    • 2
    • 2
    大肠杆菌(E. Coli)
    标记
    This E2F2 protein is labelled with His tag.
    序列
    Ala 65-Asn 437
    产品特性
    A DNA sequence encoding the Human E2F2 protein (Q14209) (Ala 65-Asn 437) was expressed with a N-His tag.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product E2F2 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    12 months
  • 抗原
    E2F2 (E2F Transcription Factor 2 (E2F2))
    别名
    E2F2 (E2F2 产品)
    别名
    E2F-2 Protein, CG1071 Protein, Dmel\\CG1071 Protein, E2F Protein, E2F2 Protein, dE2F-2 Protein, dE2F2 Protein, dE2f2 Protein, de2f2 Protein, e2f2 Protein, 9230110J10 Protein, E130207A07 Protein, fb40b03 Protein, wu:fb40b03 Protein, E2F transcription factor 2 Protein, si:ch211-160f23.5 Protein, E2F2 Protein, E2f2 Protein, si:ch211-160f23.5 Protein
    背景

    Abbreviation: E2F2

    Target Synonym: Transcription factor E2F2,E2F2,

    Background: E2F-2 (viral E2-associated factor 2) is a 50?55 kDa member of the E2F/DP family of transcription factors. It is principally expressed by placenta, and forms a DNA?activating E2F heterodimeric complex with DP-1 or -2. This complex, when active, promotes cell cycle progression. In quiescent cells, association with the retinoblastoma-tumor suppressor gene product termed pRB suppresses its activity. Human E2F?2 is 437 amino acids (aa) in length and contains a CDK2 binding region (aa 65?105), a DNA?binding domain (aa 107?196), a dimerization segment (aa 197?289), a transactivation region (aa 359?437), and a pRB binding domain (aa 410?427). There are two potential alternate start sites at Met197 and Met342, and one splice variant that shows a two aa substitution for aa 349?437.

    分子量

    Calculated MW: 40.92 kDa

    Observed MW: 55 kDa

    UniProt
    Q14209
    途径
    Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication
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