FGF18 Protein (AA 31-207) (His tag)
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- 抗原 See all FGF18 蛋白
- FGF18 (Fibroblast Growth Factor 18 (FGF18))
- 蛋白类型
- Recombinant
- 产品特性
- AA 31-207
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This FGF18 protein is labelled with His tag.
- 序列
- Val 31-Ala 207
- 产品特性
- A DNA sequence encoding the Human FGF18 protein (O76093) (Val 31-Ala 207) was expressed with a C-His tag.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product FGF18 蛋白
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Fibroblast Growth Factor 18 (FGF18) (Active) protein
FGF18 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Fibroblast Growth Factor 18 (FGF18) (AA 28-207) protein (His tag)FGF18 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Fibroblast Growth Factor 18 (FGF18) (AA 28-207) protein (His tag)FGF18 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Fibroblast Growth Factor 18 (FGF18) (AA 29-207) protein (GST tag)FGF18 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- FGF18 (Fibroblast Growth Factor 18 (FGF18))
- 别名
- FGF18 (FGF18 产品)
- 别名
- FGF-18 Protein, ZFGF5 Protein, D130055P09Rik Protein, fgf18 Protein, FGF18 Protein, fgf18l Protein, fibroblast growth factor 18 Protein, fibroblast growth factor 18a Protein, fibroblast growth factor 18b Protein, FGF18 Protein, Fgf18 Protein, fgf18a Protein, Tsp_09844 Protein, fgf18b Protein
- 背景
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Abbreviation: FGF18
Target Synonym: FGFI,zFGF5
Background: Fibroblast Growth Factor 18 (FGF-18) is a 20 kDa protein that plays an important role in skeletal development and bone homeostasis . Mature human FGF-18 shares 99 % amino acid sequence identity with mouse and rat FGF-18 . It is expressed in embryonic somites and the neural fold , adult lung , cerebellar and hippocampal neurons , hair follicle root sheath cells , and osteogenic mesenchymal cells . FGF-18 binds to FGF R2c, FGF R3c as well as the Golgi protein GLG1 and induces the proliferation of astrocytes and microglia, vascular endothelial cells, dermal fibroblasts, papilla cells, and keratinocytes . FGF-18 is required for normal skeletal development . It recruits osteoclasts and osteoblasts to the growth plate, promotes osteoclast formation and function, inhibits osteoblast differentiation, promotes skeletal vascularization, and induces chondrocyte hypertrophy and cartilage matrix formation.
- 分子量
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Calculated MW: 19.36 kDa
Observed MW: 23 kDa
- UniProt
- O76093
- 途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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