MAP4K2 Protein (AA 501-812) (His tag)
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- 抗原 See all MAP4K2 蛋白
- MAP4K2 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 501-812
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This MAP4K2 protein is labelled with His tag.
- 序列
- Ile 501-Tyr 812
- 产品特性
- A DNA sequence encoding the Human MAP4K2 protein (Q12851-2) (Ile 501-Tyr 812) was expressed with a N-His&C-His.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product MAP4K2 蛋白
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Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2) (AA 1-820) protein (GST tag)
MAP4K2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2) protein (GST tag,His tag)MAP4K2 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 87 % as determined by reducing SDS-PAGE.
Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2) protein (Myc-DYKDDDDK Tag)MAP4K2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- MAP4K2 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2))
- 别名
- MAP4K2 (MAP4K2 产品)
- 别名
- BL44 Protein, GCK Protein, RAB8IP Protein, AI385662 Protein, Rab8ip Protein, MAP4K2 Protein, dZ150L22.2 Protein, map4k2l Protein, map4k2l-2 Protein, map4k3l Protein, si:dz150l22.2 Protein, si:dz263j20.1 Protein, zgc:136670 Protein, mitogen-activated protein kinase kinase kinase kinase 2 Protein, mitogen activated protein kinase kinase kinase kinase 2 Protein, MAP4K2 Protein, Map4k2 Protein, LOC103346779 Protein, map4k2 Protein
- 背景
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Abbreviation: MAP4K2
Target Synonym: BL44;GCK;MAP4K2;RAB8IP
Background: Mitogen-activated protein kinase kinase kinase kinase 2, also known as B lymphocyte serine/threonine-protein kinase, Germinal center kinase, MAPK/ERK kinase kinase kinase 2, MEK kinase kinase 2, Rab8-interacting protein and MAP4K2, is a cytoplasm and peripheral membrane protein which belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family and STE20 subfamily. MAP4K2 contains one CNH domain and one protein kinase domain. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. MAP4K2 can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. It is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1 / MEKK1. MAP4K2 enhances MAP3K1 oligomerization, which may relieve amino-terminal mediated MAP3K1 autoinhibition and lead to activation following autophosphorylation. It may also play a role in the regulation of vesicle targeting or fusion.
- 分子量
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Calculated MW: 34.21 kDa
Observed MW: 35 kDa
- UniProt
- Q12851-2
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