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MAP4K5 Protein (AA 601-846) (His tag)

MAP4K5 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7505301
发货至: 中国
  • 抗原 See all MAP4K5 蛋白
    MAP4K5 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 5 (MAP4K5))
    蛋白类型
    Recombinant
    产品特性
    AA 601-846
    宿主
    • 7
    • 3
    资源
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This MAP4K5 protein is labelled with His tag.
    序列
    Phe 601-Tyr 846
    产品特性
    A DNA sequence encoding the Human MAP4K5 protein (Q9Y4K4) (Phe 601-Tyr 846) was expressed with a N-His&C-His.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product MAP4K5 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    12 months
  • 抗原
    MAP4K5 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 5 (MAP4K5))
    别名
    MAP4K5 (MAP4K5 产品)
    别名
    GCKR Protein, KHS Protein, KHS1 Protein, MAPKKKK5 Protein, 4432415E19Rik Protein, RGD1562028 Protein, fl74c10 Protein, wu:fl74c10 Protein, zgc:55719 Protein, zgc:55985 Protein, mitogen-activated protein kinase kinase kinase kinase 5 Protein, mitogen-activated protein kinase kinase kinase kinase 5 S homeolog Protein, MAP4K5 Protein, Map4k5 Protein, map4k5 Protein, map4k5.S Protein
    背景

    Abbreviation: MAP4K5

    Target Synonym: GCKR;KHS;KHS1;MAPKKKK5

    Background: Mitogen-activated protein kinase kinase kinase kinase 5, also known as Kinase homologous to SPS1/STE20, MAPK/ERK kinase kinase kinase 5, MEK kinase kinase 5 and MAP4K5, is a cytoplasm protein which belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family and STE20 subfamily. MAP4K5 is ubiquitously expressed in all tissues examined, with high levels in the ovary, testis and prostate. It contains one CNH domain and one protein kinase domain. MAP4K5 is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. MAP4K5 has been shown to interact with CRKL and TRAF2. This kinase was shown to activate Jun kinase in mammalian cells. MAP4K5 is an early component of MAP kinase signal cascades. It may play a role in the response to environmental stress. MAP4K5 appears to act upstream of the JUN N-terminal pathway.

    分子量

    Calculated MW: 26.95 kDa

    Observed MW: 35 kDa

    UniProt
    Q9Y4K4
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