MCM8 Protein (AA 1-250) (His tag)
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- 抗原 See all MCM8 蛋白
- MCM8 (Minichromosome Maintenance Deficient 8 (MCM8))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-250
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This MCM8 protein is labelled with His tag.
- 序列
- Met 1-Ser 250
- 产品特性
- A DNA sequence encoding the Human MCM8 protein (Q9UJA3) (Met 1-Ser 250) was expressed with a C-His,N-His.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product MCM8 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- MCM8 (Minichromosome Maintenance Deficient 8 (MCM8))
- 别名
- MCM8 (MCM8 产品)
- 别名
- C20orf154 Protein, dJ967N21.5 Protein, 5730432L01Rik Protein, minichromosome maintenance 8 homologous recombination repair factor Protein, minichromosome maintenance 8 homologous recombination repair factor L homeolog Protein, MCM8 Protein, Mcm8 Protein, mcm8.L Protein
- 背景
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Abbreviation: MCM8
Target Synonym: DNA helicase MCM8,MCM8,Minichromosome maintenance 8
Background: Component of the MCM8-MCM9 complex, a complex involved in homologous recombination repair following DNA interstrand cross-links and plays a key role during gametogenesis. The MCM8-MCM9 complex probably acts as a hexameric helicase downstream of the Fanconi anemia proteins BRCA2 and RAD51 and is required to process aberrant forks into homologous recombination substrates and to orchestrate homologous recombination with resection, fork stabilization and fork restart.
- 分子量
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Calculated MW: 27.39 kDa
Observed MW: 35 kDa
- UniProt
- Q9UJA3-1
- 途径
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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