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MCM8 Protein (AA 1-250) (His tag)

MCM8 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7505291
发货至: 中国
  • 抗原 See all MCM8 蛋白
    MCM8 (Minichromosome Maintenance Deficient 8 (MCM8))
    蛋白类型
    Recombinant
    产品特性
    AA 1-250
    宿主
    • 3
    • 1
    资源
    • 2
    • 2
    大肠杆菌(E. Coli)
    标记
    This MCM8 protein is labelled with His tag.
    序列
    Met 1-Ser 250
    产品特性
    A DNA sequence encoding the Human MCM8 protein (Q9UJA3) (Met 1-Ser 250) was expressed with a C-His,N-His.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product MCM8 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    12 months
  • 抗原
    MCM8 (Minichromosome Maintenance Deficient 8 (MCM8))
    别名
    MCM8 (MCM8 产品)
    别名
    C20orf154 Protein, dJ967N21.5 Protein, 5730432L01Rik Protein, minichromosome maintenance 8 homologous recombination repair factor Protein, minichromosome maintenance 8 homologous recombination repair factor L homeolog Protein, MCM8 Protein, Mcm8 Protein, mcm8.L Protein
    背景

    Abbreviation: MCM8

    Target Synonym: DNA helicase MCM8,MCM8,Minichromosome maintenance 8

    Background: Component of the MCM8-MCM9 complex, a complex involved in homologous recombination repair following DNA interstrand cross-links and plays a key role during gametogenesis. The MCM8-MCM9 complex probably acts as a hexameric helicase downstream of the Fanconi anemia proteins BRCA2 and RAD51 and is required to process aberrant forks into homologous recombination substrates and to orchestrate homologous recombination with resection, fork stabilization and fork restart.

    分子量

    Calculated MW: 27.39 kDa

    Observed MW: 35 kDa

    UniProt
    Q9UJA3-1
    途径
    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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