HRAS Protein (AA 1-186) (His tag)
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- 抗原 See all HRAS 蛋白
- HRAS (HRas proto-oncogene, GTPase (HRAS))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-186
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This HRAS protein is labelled with His tag.
- 序列
- Met 1-Cys 186
- 产品特性
- A DNA sequence encoding the HumanHRAS/GTPase Hras protein (P01112) (Met 1-Cys 186) was expressed with a N-His tag.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product HRAS 蛋白
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HRas proto-oncogene, GTPase (HRAS) (AA 1-189) protein (GST tag)
HRAS 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
HRas proto-oncogene, GTPase (HRAS) (AA 80-179) protein (GST tag)HRAS 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
HRas proto-oncogene, GTPase (HRAS) (AA 2-186) protein (His tag)HRAS 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
HRas proto-oncogene, GTPase (HRAS) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)HRAS 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- HRAS (HRas proto-oncogene, GTPase (HRAS))
- 别名
- HRAS (HRAS 产品)
- 别名
- C-BAS/HAS Protein, C-H-RAS Protein, C-HA-RAS1 Protein, CTLO Protein, H-RASIDX Protein, HAMSV Protein, HRAS1 Protein, K-RAS Protein, N-RAS Protein, RASH1 Protein, hras Protein, zgc:110250 Protein, HRAS Protein, H-RAS Protein, c-H-ras Protein, H-Ras Protein, K-Ras Protein, hras1 Protein, rash1 Protein, ras Protein, N-Ras Protein, c-bas/has Protein, H-ras Protein, Ha-ras Protein, Harvey-ras Protein, Hras-1 Protein, Kras2 Protein, c-Ha-ras Protein, c-rasHa Protein, hrasl Protein, zgc:110734 Protein, HRas proto-oncogene, GTPase Protein, v-Ha-ras Harvey rat sarcoma viral oncogene homolog a Protein, neuroblastoma RAS viral (v-ras) oncogene homolog pseudogene Protein, Harvey rat sarcoma viral oncogene homolog L homeolog Protein, Harvey rat sarcoma viral oncogene homolog Protein, Harvey rat sarcoma virus oncogene Protein, NRAS proto-oncogene, GTPase Protein, -Ha-ras Harvey rat sarcoma viral oncogene homolog b Protein, HRAS Protein, hrasa Protein, LOC733587 Protein, Hras Protein, hras.L Protein, hras Protein, NRAS Protein, hrasb Protein
- 背景
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Abbreviation: HRAS,GTPase Hras
Target Synonym: C-BAS/HAS,C-H-RAS,C-HA-RAS1,CTLO,H-RASIDX,HAMSV,HRAS1,p21ras,RASH1
Background: HRas, also known as HRAS, belongs to the small GTPase superfamily, Ras family and is widely expressed. It functions in signal transduction pathways. HRas can bind GTP and GDP, and they have intrinsic GTPase activity. It undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Defects in HRAS are the cause of faciocutaneoskeletal syndrome (FCSS). FCSS is arare condition characterized by prenatally increased growth, postnatal growth deficiency, mental retardation, distinctive facial appearance, cardiovascular abnormalities, tumor predisposition, skin and musculoskeletal abnormalities. Defects in HRAS also can cause congenital myopathy with excess of muscle spindles. HRAS deficiency may be a cause of susceptibility to Hurthle cell thyroid carcinoma. It has been shown that defects in HRAS can cause susceptibility to bladder cancer which is a malignancy
- 分子量
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Calculated MW: 20.35 kDa
Observed MW: 25 kDa
- UniProt
- P01112
- 途径
- p53 Pathway, MAPK Pathway, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Autophagy, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling, BCR Signaling
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