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SCO2 Protein (AA 42-266) (His tag)

SCO2 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7505240
发货至: 中国
  • 抗原 See all SCO2 蛋白
    SCO2 (SCO2 Cytochrome C Oxidase Assembly Protein (SCO2))
    蛋白类型
    Recombinant
    产品特性
    AA 42-266
    宿主
    • 3
    • 1
    资源
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This SCO2 protein is labelled with His tag.
    序列
    Gly 42-Ser 266
    产品特性
    A DNA sequence encoding the Human SCO2 protein (O43819) (Gly 42-Ser 266) was expressed with aN-His&C-His tag.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product SCO2 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    12 months
  • 抗原
    SCO2 (SCO2 Cytochrome C Oxidase Assembly Protein (SCO2))
    别名
    SCO2 (SCO2 产品)
    别名
    CEMCOX1 Protein, MYP6 Protein, SCO1L Protein, SCO cytochrome oxidase deficient homolog 2 (yeast) Protein, SCO2 cytochrome c oxidase assembly protein Protein, SCO2, cytochrome c oxidase assembly protein Protein, SCO2 Protein, Sco2 Protein
    背景

    Abbreviation: SCO2

    Target Synonym: Protein SCO2 homolog,mitochondrial,SCO2,

    Background: Acts as a copper chaperone, transporting copper to the Cu(A) site on the cytochrome c oxidase subunit II (COX2).Defects in SCO2 are the cause of fatal infantile cardioencephalomyopathy with cytochrome c oxidase deficiency (FIC) . This disease is characterized by hypertrophic cardiomyopathy, lactic acidosis, and gliosis. Heart and skeletal muscle show reductions in cytochrome c oxidase (COX) activity, whereas liver and fibroblasts show mild COX deficiencies.

    分子量

    Calculated MW: 24.64 kDa

    Observed MW: 30 kDa

    UniProt
    O43819
    途径
    Transition Metal Ion Homeostasis, Warburg Effect
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