SOCS2 Protein (AA 1-198) (His tag)
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- 抗原 See all SOCS2 蛋白
- SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-198
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This SOCS2 protein is labelled with His tag.
- 序列
- Met 1-Val 198
- 产品特性
- A DNA sequence encoding the Human SOCS2 protein (O14508) (Met 1-Val 198) was expressed with a N-His&C-His tag.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product SOCS2 蛋白
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Suppressor of Cytokine Signaling 2 (SOCS2) (AA 1-198) protein (GST tag)
SOCS2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Suppressor of Cytokine Signaling 2 (SOCS2) (AA 99-198) protein (GST tag)SOCS2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))
- 别名
- SOCS2 (SOCS2 产品)
- 别名
- CIS2 Protein, Cish2 Protein, SOCS-2 Protein, SSI-2 Protein, SSI2 Protein, STATI2 Protein, Cish1 Protein, Socs-1 Protein, Socs-2 Protein, si:dkey-202b22.1 Protein, socs2 Protein, cis2 Protein, ssi2 Protein, cish2 Protein, ssi-2 Protein, socs-2 Protein, stati2 Protein, 8030460M17 Protein, AI527257 Protein, AW108012 Protein, D130043N08Rik Protein, JAB Protein, hg Protein, Cradd Protein, Socs2 Protein, suppressor of cytokine signaling 2 Protein, suppressor of cytokine signaling 1 Protein, death domain-containing protein CRADD Protein, suppressor of cytokine signaling 2 S homeolog Protein, SOCS2 Protein, Socs1 Protein, Socs2 Protein, socs2 Protein, LOC100716104 Protein, socs2.S Protein
- 背景
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Abbreviation: SOCS2
Target Synonym: Suppressor of cytokine signaling 2,SOCS2,Cytokine-inducible SH2 protein 2,STAT-induced STAT inhibitor 2
Background: SOCS-2 (Suppressor of cytokine signaling 2, also CIS-2 and SSI-2) is a 25 kDa member of the SOCS family of proteins. It is an SH2-domain containing cytoplasmic adaptor protein expressed by multiple cell types. It blocks receptor signaling by binding to phosphorylated tyrosines in the cytoplasmic domain of select receptors, including the receptors for leptin, IGF-I and GH. Human SOCS-2 is 198 amino acids (aa) in length and contains one SH2 domain (aa 48?156) and a SOCS box (aa 160?198) that mediates interaction with elongin B or C of the E3 ubiquitin ligase complex. There is one splice variant that shows an Arg-rich eight aa substitution for aa 31?39. Full-length SOCS-2 is 94 % and 96 % aa identical to mouse and porcine SOCS-2, respectively.
- 分子量
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Calculated MW: 21.67 kDa
Observed MW: 25 kDa
- UniProt
- O14508
- 途径
- JAK/STAT Signaling, Response to Growth Hormone Stimulus
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