GADD45A Protein (AA 1-165) (His tag)
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- 抗原 See all GADD45A 蛋白
- GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-165
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This GADD45A protein is labelled with His tag.
- 序列
- Met 1-Arg 165
- 产品特性
- A DNA sequence encoding the Human GADD45A protein (P24522 ) (1M-165R) was expressed with N-His tag.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product GADD45A 蛋白
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Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) (AA 76-165) protein (GST tag)
GADD45A 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) (AA 1-165) protein (GST tag)GADD45A 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) (AA 1-165), (full length) protein (His-SUMO Tag)GADD45A 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) protein (Myc-DYKDDDDK Tag)GADD45A 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))
- 别名
- GADD45A (GADD45A 产品)
- 别名
- MGC53491 Protein, zgc:91795 Protein, gadd45a Protein, GADD45A Protein, ddit1 Protein, gadd45 Protein, GADD45 Protein, AA545191 Protein, Ddit1 Protein, DDIT1 Protein, Gadd45 Protein, growth arrest and DNA damage inducible alpha L homeolog Protein, growth arrest and DNA-damage-inducible, alpha, b Protein, growth arrest and DNA damage inducible alpha Protein, growth arrest and DNA damage-inducible protein 45 Protein, growth arrest and DNA-damage-inducible 45 alpha Protein, growth arrest and DNA-damage-inducible, alpha Protein, gadd45a.L Protein, gadd45ab Protein, GADD45A Protein, gadd45a Protein, GADD45 Protein, Gadd45a Protein
- 背景
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Abbreviation: GADD45A
Target Synonym: Growth arrest and DNA damage-inducible protein GADD45 alpha,GADD45A,DNA damage-inducible transcript 1 protein,
Background: GADD45 alpha (Growth arrest and DNA damage-inducible protein 45 alpha) is a 19 kDa member of the GADD45 family of proteins. It is ubiquitously expressed, and induced by DNA damage. Upon induction, GADD45 alpha binds to PCNA, stimulates DNA excision repair, and initiates G2 cell cycle arrest. Human GADD45 alpha is 165 amino acids (aa) in length. It is reported to dimerize with GADD45-beta and -gamma, and to homo-dimerize, -trimerize and -tetramerize via residues 33?61 and 133?165. There is one splice variant that shows a Ser substitution for aa 14?49. GADD45 alpha is 55 % aa identical to GADD45-beta and -gamma, and shares 94 % aa identity with mouse GADD45 alpha.
- 分子量
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Calculated MW: 18.04 kDa
Observed MW: 23 kDa
- UniProt
- P24522
- 途径
- p53 Pathway, Cell Division Cycle
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