APC Protein (AA 2712-2843) (His tag)
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- 抗原 See all APC 蛋白
- APC (Adenomatous Polyposis Coli (APC))
- 蛋白类型
- Recombinant
- 产品特性
- AA 2712-2843
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This APC protein is labelled with His tag.
- 序列
- Pro 2712-Val 2843
- 产品特性
- A DNA sequence encoding the Human APC protein (P25054) (Pro 2712-Val 2843) was expressed with N-His tag.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product APC 蛋白
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Adenomatous Polyposis Coli (APC) (AA 1089-1329) protein (His tag)
APC 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Adenomatous Polyposis Coli (APC) (AA 2744-2843) protein (GST tag)APC 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Adenomatous Polyposis Coli (APC) proteinAPC 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % WB, SDS, ELISA, IP
Adenomatous Polyposis Coli (APC) proteinAPC 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % WB, SDS, ELISA, IP
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- APC (Adenomatous Polyposis Coli (APC))
- 别名
- APC (APC 产品)
- 别名
- dp2 Protein, dp3 Protein, fap Protein, fpc Protein, xapc Protein, dp2.5 Protein, AI047805 Protein, AU020952 Protein, AW124434 Protein, CC1 Protein, Min Protein, mAPC Protein, BTPS2 Protein, DP2 Protein, DP2.5 Protein, DP3 Protein, GS Protein, PPP1R46 Protein, RATAPC Protein, APC1 Protein, APC, WNT signaling pathway regulator Protein, adenomatous polyposis coli Protein, adenomatous polyposis coli protein, putative Protein, adenomatosis polyposis coli Protein, adenomatous polyposis coli L homeolog Protein, APC Protein, apc Protein, Smp_139190 Protein, Apc Protein, apc.L Protein
- 背景
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Abbreviation: APC
Target Synonym: Adenomatous polyposis coli protein,APC, Deleted in polyposis 2.5
Background: APC is a ubiquitous, tumor-suppressor protein that is mutated in most colon cancers, generally resulting in a gene product that is truncated in the carboxy terminal region. APC contains several binding domains. The region used as an immunogen overlaps the EB1, DLG (PDZ sequence), and PSD-93 domains. These domains bind microtubules, mitotic spindles, and F-actin and are involved in cell cycle, division, and migration. The immunogen does not include the beta -catenin-binding region, which antagonizes Wnt signaling. The human APC amino acid sequence used as immunogen is 83 % and 86 % identical to mouse and rat APC, respectively.
- 分子量
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Calculated MW: 14.41 kDa
Observed MW: 18 kDa
- UniProt
- P25054
- 途径
- WNT signaling, Stem Cell Maintenance, Cell-Cell Junction Organization
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