CD147 Protein (AA 138-323) (His tag)
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- 抗原 See all CD147 (BSG) 蛋白
- CD147 (BSG) (Basigin (Ok Blood Group) (BSG))
- 蛋白类型
- Recombinant
- 产品特性
- AA 138-323
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This CD147 protein is labelled with His tag.
- 序列
- Glu 138-Ala 323
- 产品特性
- A DNA sequence encoding the Human CD147/BSG/Basigin protein (P35613) (Glu 138-Ala 323) was expressed with N-His tag.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product BSG 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- CD147 (BSG) (Basigin (Ok Blood Group) (BSG))
- 别名
- CD147 (BSG 产品)
- 别名
- EMMPRIN Protein, RPE7 Protein, 5F7 Protein, CD147 Protein, M6 Protein, OK Protein, TCSF Protein, AI115436 Protein, AI325119 Protein, HT-7 Protein, 5A11 Protein, CE9 Protein, HT7 Protein, Ox47R Protein, basignin Protein, wu:fb26a05 Protein, wu:fo98e12 Protein, bsg Protein, prso03 Protein, basigin (Ok blood group) Protein, basigin Protein, basigin (Ok blood group) S homeolog Protein, BSG Protein, Bsg Protein, bsg Protein, bsg.S Protein
- 背景
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Abbreviation: CD147,BSG,Basigin
Target Synonym: Basigin,5F7,Collagenase Stimulatory Factor,Extracellular Matrix Metalloproteinase Inducer,EMMPRIN,Leukocyte Activation Antigen M6,OK Blood Group Antigen,Tumor Cell-Derived Collagenase Stimulatory Factor,TCSF,CD147,BSG
Background: CD147/EMMPRIN (Extracellular Matrix Metalloproteinase Inducer), also known as Basigin (BSG), is a transmembrane glycoprotein with different forms resulted from different modes of glycosylation and N-terminal sequence variants. It is a member of the immunoglobulin superfamily with homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. This protein play important roles in variety of events including spermatogenesis, embryo implantation, neural network formation. CD147 induces the production and release of matrix metalloproteinases (MMP) in the surrounding mesenchymal cells and tumor cells, and thereby promotes invasion, metastasis, growth and survival of malignant cells. Furthermore, CD147 also serves as a receptor for extracellular cyclophilinthe and its association with integrins might be important in signal transduction. Recently, CD147 displays increased expression in many cancers, and it has been previously demonstrated to participate in cancer metastasis and progression. Thus, CD147 and its antibody are used as an effective treatment for malignant cancers.
- 分子量
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Calculated MW: 20.35 kDa
Observed MW: 25 kDa
- UniProt
- P35613
- 途径
- S100 Proteins
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