IGF1R Protein (AA 741-1036) (His tag)
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- 抗原 See all IGF1R 蛋白
- IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
- 蛋白类型
- Recombinant
- 产品特性
- AA 741-1036
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This IGF1R protein is labelled with His tag.
- 序列
- Asp 741-Asn 1036
- 产品特性
- A DNA sequence encoding the Human IGF1R/CD221/IGF-I R protein (P08069) (741D-1036N) was expressed with N-His.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product IGF1R 蛋白
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Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 31-932) protein (His-Avi Tag)
IGF1R 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 31-932) protein (His-Avi Tag,Biotin)IGF1R 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 31-932) (Active) protein (His tag)IGF1R 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 31-936) protein (His tag)IGF1R 宿主: 小鼠 宿主: Mammalian Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 741-935) protein (His-IF2DI Tag)IGF1R 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 31-932) protein (His tag)IGF1R 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 761-870) protein (GST tag)IGF1R 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 741-935) protein (His-DYKDDDDK-Strep II Tag)IGF1R 宿主: 人 宿主: HEK-293T Cells Recombinant WB, SDS, ELISA, PI
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
- 别名
- IGF1R (IGF1R 产品)
- 别名
- CMT2N Protein, CD221 Protein, IGFIR Protein, IGFR Protein, JTK13 Protein, IGFIRC Protein, IGFR1 Protein, IGF-1R Protein, IGF1R Protein, DKFZp469I0618 Protein, igf-1r Protein, xIGF-1R Protein, xIGFR Protein, xigf1r Protein, A330103N21Rik Protein, D930020L01 Protein, hyft Protein, igf-ir Protein, IGF-IR Protein, IGF-IRb Protein, wu:fb03h06 Protein, IGF-IRa Protein, sb:eu1090 Protein, wu:fi20b10 Protein, alanyl-tRNA synthetase Protein, insulin like growth factor 1 receptor Protein, insulin-like growth factor 1 receptor Protein, insulin-like growth factor 1 Protein, insulin-like growth factor I receptor Protein, insulin like growth factor 1 receptor S homeolog Protein, insulin-like growth factor 1b receptor Protein, insulin-like growth factor 1a receptor Protein, AARS Protein, IGF1R Protein, Igf1r Protein, igf1r Protein, Igf1 Protein, LOC780503 Protein, LOC100136427 Protein, igf1r.S Protein, igf1rb Protein, igf1ra Protein
- 背景
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Abbreviation: IGF1R,CD221,IGF-I R
Target Synonym: CD221 antigen,CD221,IGF1R,IGF-1R,IGF-I R,IGF-I receptor,IGFIR,IGF-IR,IGFR,insulin-like growth factor 1 receptor,JTK13
Background: The insulin-like growth factor-1 receptor (IGF1R) is a transmembrane tyrosine kinase involved in several biological processes including cell proliferation, differentiation, DNA repair, and cell survival. This a disulfide-linked heterotetrameric transmembrane protein consisting of two α and two β subunits, and among which, the α subunit is extracellular while the β subunit has an extracellular domain, a transmembrane domain and a cytoplasmic tyrosine kinase domain. The IGF-I receptor is highly expressed in all cell types and tissues. Essentially all of the biological activities of IGF-I and II have been shown to be mediated via IGF-I R. IGF1R is an important signaling molecule in cancer cells and plays an essential role in the establishment and maintenance of the transformed phenotype. Inhibition of IGF1R signaling thus appears to be a promising strategy to interfere with the growth and survival of cancer cells, is now an attractive anti-cancer treatment target.
- 分子量
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Calculated MW: 32.45 kDa
Observed MW: 38 kDa
- UniProt
- P08069
- 途径
- RTK signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy
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