Kallikrein 2 Protein (KLK2) (AA 25-261) (His tag)
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- 抗原 See all Kallikrein 2 (KLK2) 蛋白
- Kallikrein 2 (KLK2)
- 蛋白类型
- Recombinant
- 产品特性
- AA 25-261
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This Kallikrein 2 protein is labelled with His tag.
- 序列
- Ile 25-Pro 261
- 产品特性
- A DNA sequence encoding the Human KLK2 protein (P20151) (Ile 25-Pro 261) was expressed with N-His tag.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product KLK2 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- Kallikrein 2 (KLK2)
- 别名
- KLK2 (KLK2 产品)
- 别名
- KLK2A2 Protein, hGK-1 Protein, hK2 Protein, KLK2 Protein, Ton Protein, rGK-2 Protein, Klk2 Protein, kallikrein related peptidase 2 Protein, kallikrein-related peptidase 2 Protein, kallikrein-2 Protein, kallikrein 1-related peptidase C2 Protein, KLK2 Protein, LOC748637 Protein, Klk1c2 Protein, LOC100716976 Protein
- 背景
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Abbreviation: KLK2
Target Synonym: Signal Transduction,Cell biology,Cancer
Background: Kallikrein-2 (KLK2) is a secreted serine protease that belongs to the peptidase S1 family of Kallikrein subfamily. KLK2 contains 1 peptidase S1 domain. It is highly expressed in the human prostate gland. KLK2 can cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin, but Preferential cleavages of Arg-|-Xaa bonds in small molecule substrates. It also highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-|-Xaa or Leu-|-Xaa. KLK2 is inhibited by serpins such as protein C inhibitor, antichymotrypsin, and plasminogen. KLK2 is considered to be a biomarker for prostate cancer.
- 分子量
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Calculated MW: 25.96 kDa
Observed MW: 31 kDa
- UniProt
- P20151
- 途径
- Complement System
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