MCAM Protein (AA 25-206) (His tag)
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- 抗原 See all MCAM 蛋白
- MCAM (Melanoma Cell Adhesion Molecule (MCAM))
- 蛋白类型
- Recombinant
- 产品特性
- AA 25-206
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This MCAM protein is labelled with His tag.
- 序列
- Pro 25-Ser 206
- 产品特性
- A DNA sequence encoding the Human CD146/MCAM protein (P43121) (Pro 25-Ser 206) was expressed with N-His tag.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product MCAM 蛋白
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Melanoma Cell Adhesion Molecule (MCAM) (AA 24-559) protein (His tag)
MCAM 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Melanoma Cell Adhesion Molecule (MCAM) (AA 24-563) protein (His tag)MCAM 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Melanoma Cell Adhesion Molecule (MCAM) (AA 1-646) protein (GST tag)MCAM 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Melanoma Cell Adhesion Molecule (MCAM) (AA 24-646) protein (His-DYKDDDDK-Strep II Tag)MCAM 宿主: 人 宿主: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- MCAM (Melanoma Cell Adhesion Molecule (MCAM))
- 别名
- CD146 (MCAM 产品)
- 别名
- CD146 Protein, MUC18 Protein, Muc18 Protein, 1-gicerin Protein, AV025631 Protein, CD149 Protein, s-endo Protein, s-gicerin Protein, cd146 Protein, gicerin Protein, id:ibd3512 Protein, mcam Protein, MCAM Protein, melanoma cell adhesion molecule Protein, melanoma cell adhesion molecule b Protein, MCAM Protein, Mcam Protein, mcamb Protein
- 背景
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Abbreviation: CD146,MCAM
Target Synonym: CD146,MUC18
Background: The CD146 antigen, also known as melanoma cell adhesion molecule (MCAM) and MUC18, is an integral membrane glycoprotein belonging to the immunoglobulin superfamily. CD146 contains the characteristic immunoglobulin-like domains (V-V-C2-C2-C2), a transmembrane region and a short cytoplasmic tail. The CD146 expression is detected in endothelial cells in vascular tissue throughout the body, and plays a role in cell adhesion, as well as in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. As a Ca2+-independent cell adhesion molecule involved in heterophilic cell to cell interactions and a surface receptor, CD146 triggers tyrosine phosphorylation of FYN and PTK2 and subsequently induced signal transduction, proteolysis, or immune recognition. This protein is also expressed predominantly on metastatic lesions and advanced primary tumours, and thus has been suggested to play an important role in tumour progression and the development of metastasis in certain human carcinomas.
- 分子量
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Calculated MW: 19.91 kDa
Observed MW: 25 kDa
- UniProt
- P43121
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