COL2A1 Protein (AA 1-268) (GST-His-Tag)
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- 抗原 See all COL2A1 蛋白
- COL2A1 (Collagen, Type II, alpha 1 (COL2A1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-268
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This COL2A1 protein is labelled with GST-His-Tag.
- 序列
- Met 1-Leu 268
- 产品特性
- A DNA sequence encoding the Human COL2A1 protein (P02458-3) (Met 1-Leu 268) was expressed with a N-GST&C-His.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product COL2A1 蛋白
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Collagen, Type II, alpha 1 (COL2A1) (AA 1-268) protein (GST tag)
COL2A1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- COL2A1 (Collagen, Type II, alpha 1 (COL2A1))
- 别名
- COL2A1 (COL2A1 产品)
- 别名
- ANFH Protein, AOM Protein, COL11A3 Protein, SEDC Protein, Col2 Protein, Col2a Protein, Col2a-1 Protein, Del1 Protein, Dmm Protein, Lpk Protein, M100856 Protein, Rgsc856 Protein, CG2A1A Protein, COLLII Protein, col2a1a Protein, CB11 Protein, col2a1 Protein, coll2a1 Protein, fb38c06 Protein, fc10c01 Protein, wu:fb38c06 Protein, wu:fc10c01 Protein, collagen type II alpha 1 chain Protein, collagen, type II, alpha 1 Protein, collagen, type II, alpha 1 L homeolog Protein, collagen, type II, alpha 1 S homeolog Protein, collagen, type II, alpha 1a Protein, COL2A1 Protein, Col2a1 Protein, col2a1 Protein, col2a1.L Protein, col2a1.S Protein, col2a1a Protein
- 背景
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Abbreviation: COL2A1
Target Synonym: ANFH,AOM,COL11A3,SEDC,STL1
Background: COL2A1 is the alpha-1 chain of type II collagen which is a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this protein are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. Type II collagen is specific for cartilaginous tissues. Thus COL2A1 is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces. The regulation of COL2A1, likely results from a balance of both positive and negative proteins. The inhibition of COL2A1 transcription following treatment of chick sternal chondrocytes with growth factors was accompanied by increased EF1 expression. Overexpression of EF1 in differentiated chondrocytes resulted in decreased expression of a reporter construct containing a collagen II promoter/enhancer insert.
- 分子量
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Calculated MW: 54.37 kDa
Observed MW: 54 kDa
- UniProt
- P02458-3
- 途径
- Sensory Perception of Sound, Growth Factor Binding
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