p21 Protein (AA 40-164) (His tag)
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- 抗原 See all p21 (CDKN1A) 蛋白
- p21 (CDKN1A) (Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A))
- 蛋白类型
- Recombinant
- 产品特性
- AA 40-164
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This p21 protein is labelled with His tag.
- 序列
- Gly 40-Pro 164
- 产品特性
- A DNA sequence encoding the Human P21 protein (P38936) (Gly 40-Pro 164) was expressed with a N-His tag.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product CDKN1A 蛋白
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Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) (AA 2-164) protein (His tag)
CDKN1A 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) (AA 2-164) protein (His-IF2DI Tag)CDKN1A 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) (AA 65-164) protein (GST tag)CDKN1A 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) (AA 1-164) protein (GST tag)CDKN1A 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)CDKN1A 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- p21 (CDKN1A) (Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A))
- 别名
- P21 (CDKN1A 产品)
- 别名
- CCND1 Protein, CDKN1A Protein, CAP20 Protein, CDKN1 Protein, CIP1 Protein, MDA-6 Protein, P21 Protein, SDI1 Protein, WAF1 Protein, p21CIP1 Protein, CDKI Protein, Cdkn1 Protein, Waf1 Protein, mda6 Protein, p21Cip1 Protein, p21WAF Protein, Cip1 Protein, UV96 Protein, p21 Protein, cip1 Protein, p16Xic2 Protein, sdi1 Protein, waf1 Protein, cap20 Protein, cdkn1 Protein, mda-6 Protein, p21cip1 Protein, si:ch1073-48m5.2 Protein, KRAS2 Protein, p21ras Protein, cyclin D1 Protein, cyclin dependent kinase inhibitor 1A Protein, cyclin-dependent kinase inhibitor 1A (P21) Protein, cyclin-dependent kinase inhibitor 1A Protein, cyclin-dependent kinase inhibitor 1A L homeolog Protein, cyclin-dependent kinase inhibitor 1 Protein, KRAS proto-oncogene, GTPase Protein, CCND1 Protein, CDKN1A Protein, Cdkn1a Protein, cdkn1a.L Protein, cki1 Protein, cdkn1a Protein, KRAS Protein
- 背景
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Abbreviation: P21
Target Synonym: CAP20,CDK-interacting protein 1,CDKI,CDKN1,CDN1A,CIP1,CDKN1A,Cyclin Dependent Kinase Inhibitor 1A,DNA Synthesis Inhibitor,MDA-6,MDA6,Melanoma differentiation-associated protein 6,P21cip1,P21waf,PIC1,SDI1,SLC12A9,WAF1
Background: May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex.
- 分子量
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Calculated MW: 13.64 kDa
Observed MW: 18 kDa
- UniProt
- P38936
- 途径
- p53 Pathway, PI3K-Akt Signaling, Cell Division Cycle, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Hepatitis C, Synthesis of DNA, Autophagy
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