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MAP1LC3A Protein (AA 1-125) (His tag)

MAP1LC3A 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7505148
发货至: 中国
  • 抗原 See all MAP1LC3A 蛋白
    MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))
    蛋白类型
    Recombinant
    产品特性
    AA 1-125
    宿主
    • 6
    • 2
    • 1
    资源
    • 6
    • 2
    • 1
    大肠杆菌(E. Coli)
    标记
    This MAP1LC3A protein is labelled with His tag.
    序列
    Met 1-Val 125
    产品特性
    A DNA sequence encoding the Human LC3A/B protein (Q9GZQ8) (Met 1-Val 125) was expressed with a N-10His tag.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product MAP1LC3A 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    12 months
  • 抗原
    MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))
    别名
    LC3A (MAP1LC3A 产品)
    别名
    ATG8E Protein, LC3 Protein, LC3A Protein, MAP1ALC3 Protein, MAP1BLC3 Protein, 1010001H21Rik Protein, 4922501H04Rik Protein, LC3a Protein, MGC69006 Protein, zgc:77094 Protein, MGC89867 Protein, MAP1LC3A Protein, map1lc3a Protein, microtubule associated protein 1 light chain 3 alpha Protein, microtubule-associated protein 1 light chain 3 alpha Protein, microtubule associated protein 1 light chain 3 alpha S homeolog Protein, MAP1LC3A Protein, Map1lc3a Protein, map1lc3a.S Protein, map1lc3a Protein
    背景

    Abbreviation: MLP3B,MAP1LC3B

    Target Synonym: MLP3B,ATG8F,Autophagy related protein LC3 A,Autophagy related ubiquitin like modifier LC3 A,Autophagy related ubiquitin like modifier LC3 B,LC3,MAP1 light chain 3 like protein 1,MAP1 light chain 3 like protein 2,MAP1A/1B light chain 3 A,MAP1A/1BLC3,MAP1ALC3,MAP

    Background: Ubiquitin-like modifier involved in formation of autophagosomal vacuoles. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. In response to cellular stress and upon mitochondria fission, binds C-18 ceramides and anchors autophagolysosomes to outer mitochondrial membranes to eliminate damaged mitochondria. While LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.

    分子量

    Calculated MW: 13.64 kDa

    Observed MW: 18 kDa

    UniProt
    Q9GZQ8
    途径
    Autophagy
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