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NEDD8 Protein (AA 1-76) (His tag)

NEDD8 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7505146
发货至: 中国
  • 抗原 See all NEDD8 蛋白
    NEDD8 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8))
    蛋白类型
    Recombinant
    产品特性
    AA 1-76
    宿主
    • 5
    • 1
    • 1
    • 1
    • 1
    资源
    • 5
    • 3
    • 1
    大肠杆菌(E. Coli)
    标记
    This NEDD8 protein is labelled with His tag.
    序列
    Met 1-Gly 76
    产品特性
    A DNA sequence encoding the Human NEDD8 protein (Q15843) (Met 1-Gly 76) was expressed with a N-10His.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product NEDD8 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    12 months
  • 抗原
    NEDD8 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8))
    别名
    NEDD8 (NEDD8 产品)
    别名
    NEDD-8 Protein, Rub1 Protein, CG10679 Protein, Dmel\\CG10679 Protein, NEDD8 Protein, dNEDD8 Protein, nedd8 Protein, ubiquitin Protein, si:zc14a17.5 Protein, GB17785 Protein, DDBDRAFT_0218116 Protein, DDBDRAFT_0238041 Protein, DDB_0218116 Protein, DDB_0238041 Protein, nedd8.S Protein, neural precursor cell expressed, developmentally down-regulated 8 Protein, neural precursor cell expressed, developmentally down-regulated gene 8 Protein, CG10679 gene product from transcript CG10679-RB Protein, Nedd8 Protein, ubiquitin-like protein Nedd8 Protein, neural precursor cell expressed, developmentally down-regulated 8 L homeolog Protein, NEDD8 Protein, Nedd8 Protein, nedd8 Protein, nedd8.L Protein
    背景

    Abbreviation: NEDD8

    Target Synonym: Neural precursor cell expressed developmentally down-regulated protein 8,NEDD8,Neddylin,Ubiquitin-like protein Nedd8

    Background: Human NEDD8 shares 60 % amino acid sequence identity to ubiquitin. The only known substrates of NEDD8 modification are the cullin subunits of SCF ubiquitin E3 ligases. The NEDDylation of cullins is critical for the recruitment of E2 to the ligase complex, thus facilitating ubiquitin conjugation. NEDD8 modification has therefore been implicated in cell cycle progression and cytoskeletal regulation.

    分子量

    Calculated MW: 8.25 kDa

    Observed MW: 12 kDa

    UniProt
    Q15843
    途径
    Ubiquitin Proteasome Pathway
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