Estrogen Receptor alpha Protein (AA 297-554) (His tag)
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- 抗原 See all Estrogen Receptor alpha (ESR1) 蛋白
- Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 297-554
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This Estrogen Receptor alpha protein is labelled with His tag.
- 序列
- Met 297-Ser 554
- 产品特性
- A DNA sequence encoding the Human ER alpha protein (P03372) (Met 297-Ser 554) was expressed with a N-His tag.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product ESR1 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
- 别名
- ER alpha (ESR1 产品)
- 别名
- LOC398734 Protein, AA420328 Protein, AU041214 Protein, ER-alpha Protein, ER[a] Protein, ERa Protein, ERalpha Protein, ESR Protein, Estr Protein, Estra Protein, Nr3a1 Protein, NR3A1 Protein, eralpha Protein, zfER[a] Protein, ER Protein, ESRA Protein, ESTRR Protein, Era Protein, akap12 Protein, cb27 Protein, esr1 Protein, fb72g12 Protein, id:ibd1202 Protein, sb:cb27 Protein, si:ch73-192g21.1 Protein, wu:fb72g12 Protein, wu:fc21c03 Protein, Esr Protein, RNESTROR Protein, ERALPHA Protein, er Protein, esr Protein, nr3a1 Protein, XER Protein, era Protein, esra Protein, ERbeta Protein, xesr-1 Protein, xlERalpha1 Protein, xlERalpha2 Protein, ESR1 Protein, estrogen receptor 1 L homeolog Protein, estrogen receptor 1 (alpha) Protein, estrogen receptor 1 Protein, A kinase (PRKA) anchor protein 12b Protein, esr1.L Protein, Esr1 Protein, ESR1 Protein, esr1 Protein, akap12b Protein
- 背景
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Abbreviation: ER alpha
Target Synonym: Estrogen Receptor α,Estrogen Receptor,ER,ER-Alpha,Estradiol Receptor,Nuclear Receptor Subfamily 3 Group A Member 1,ESR1,ESR,NR3A1
Background: Estrogen Receptor is a major ligand-activated transcription factor belonging to the nuclear hormone receptor superfamily. Estrogen Receptor is composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but they also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.
- 分子量
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Calculated MW: 28.27 kDa
Observed MW: 31 kDa
- UniProt
- P03372
- 途径
- Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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