SNCA Protein (AA 1-140) (His tag)
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- 抗原 See all SNCA 蛋白
- SNCA (Synuclein, alpha (SNCA))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-140
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This SNCA protein is labelled with His tag.
- 序列
- Met 1-Ala 140
- 产品特性
- A DNA sequence encoding the Human Synuclein-α(SNCA) protein (P37840) (Met 1-Ala 140) was expressed with a N-His&C-His tag.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product SNCA 蛋白
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Synuclein, alpha (SNCA) (Ala53Thr-Mutant) (Active) protein
SNCA 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant SDS, WB, in vitro, in vivo Active
Synuclein, alpha (SNCA) (full length) (Active) proteinSNCA 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant SDS, WB, in vitro, in vivo Active
Synuclein, alpha (SNCA) (full length) (Active) proteinSNCA 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95% pure using SDS-PAGE analysis. SDS, WB, in vitro, in vivo Active
Synuclein, alpha (SNCA) proteinSNCA 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by SDS-PAGE
Synuclein, alpha (SNCA) (AA 1-140) protein (His tag)SNCA 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Synuclein, alpha (SNCA) (AA 1-140) protein (GST tag)SNCA 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Synuclein, alpha (SNCA) (AA 31-140) protein (GST tag)SNCA 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Synuclein, alpha (SNCA) (AA 1-139), (partial) protein (GST tag)SNCA 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 90 % SDS, ELISA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- SNCA (Synuclein, alpha (SNCA))
- 别名
- Synuclein-alpha (SNCA 产品)
- 别名
- snca Protein, MGC64356 Protein, LOC619283 Protein, NACP Protein, alphaSYN Protein, PARK1 Protein, PARK4 Protein, PD1 Protein, synuclein alpha L homeolog Protein, alpha-synuclein Protein, synuclein alpha Protein, synuclein, alpha Protein, snca.L Protein, LOC619283 Protein, SNCA Protein, Snca Protein
- 背景
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Abbreviation: Synuclein-α
Target Synonym: Vascular endothelial growth factor receptor 2,KDR,VEGFR-2,Fetal liver kinase 1,FLK-1,Kinase insert domain receptor,Protein-tyrosine kinase receptor flk-1,CD309,Flk-1,FLK1,VEGFR,VEGFR2
Background: Alpha-Synuclein (alpha-Syn), also known as NACP or SNCA, exists as at least two structural isoforms: one is helix-rich, membrane-bound form that both the N- and C-terminal regions of alpha-synuclein are tightly associated with membranes and the other is disordered, cytosolic form. Synuclein is found predominantly in the presynaptic termini, in both free or membrane-bound forms. SNCA is extensively localized in nucleus of neurons. It has been shown that alpha-Synuclein was highly expressed in the mitochondria in olfactory bulb, hippocampus, striatum, and thalamus, where the cytosolic alpha-Synuclein was also rich. Normally the unstructured soluble type of alpha-synuclein can aggregate to form insoluble fibrils in pathological conditions characterized by Lewy bodies, such as Parkinson's disease, dementia with Lewy bodies and multiple system atrophy. SNCA abnormality and mitochondrial deficiency are two major changes in the brain of patients with Parkinson's disease (PD). In addition, alpha-synuclein is an abundant component of Lewy bodies in sporadic Parkinson's disease and diffuse Lewy body disease.
- 分子量
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Calculated MW: 15.29 kDa
Observed MW: 19 kDa
- UniProt
- P37840
- 途径
- Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
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