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BDNF Protein (AA 129-247) (His tag)

BDNF 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7505123
发货至: 中国
  • 抗原 See all BDNF 蛋白
    BDNF (Brain-Derived Neurotrophic Factor (BDNF))
    蛋白类型
    Recombinant
    产品特性
    AA 129-247
    宿主
    • 21
    • 8
    • 7
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 31
    • 17
    • 3
    • 2
    • 2
    • 1
    大肠杆菌(E. Coli)
    标记
    This BDNF protein is labelled with His tag.
    序列
    His 129-Arg 247
    产品特性
    A DNA sequence encoding the Human BDNF protein (P23560) (His 129-Arg 247) was expressed with a N-His tag.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product BDNF 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    12 months
  • 抗原
    BDNF (Brain-Derived Neurotrophic Factor (BDNF))
    别名
    BDNF (BDNF 产品)
    别名
    ANON2 Protein, BULN2 Protein, bdnf-A Protein, BDNF Protein, bdnf Protein, brain derived neurotrophic factor Protein, brain-derived neurotrophic factor Protein, brain-derived neurotrophic factor L homeolog Protein, brain-derived neurotrophic factor S homeolog Protein, BDNF Protein, Bdnf Protein, bdnf Protein, bdnf.L Protein, bdnf.S Protein
    背景

    Abbreviation: BDNF

    Target Synonym: Brain-Derived Neurotrophic Factor,BDNF,Abrineurin

    Background: The precursor form of Brain-Derived Neurotrophic Factor (pro-BDNF) interacts preferentially with the pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin and induces neuronal apoptosis, whereas mature BDNF selectively binds with high affinity to the TrkB kinase receptor and promotes the survival, growth and differentiation of neurons. As proneurotrophins and mature neurotrophins elicit opposite biological effects, Pro-BDNF cleavage in the neuronal system is regulated in a specific and cell-context dependent manner. Pro-BDNF plays important role in negative regulation of neurotrophic actions in the brain.

    分子量

    Calculated MW: 12.98 kDa

    Observed MW: 15 kDa

    UniProt
    P23560
    途径
    RTK signaling, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity
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