APOH Protein (AA 263-345) (His tag)
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- 抗原 See all APOH 蛋白
- APOH (Apolipoprotein H (Beta-2-Glycoprotein I) (APOH))
- 蛋白类型
- Recombinant
- 产品特性
- AA 263-345
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This APOH protein is labelled with His tag.
- 序列
- Ser 263-Cys 345
- 产品特性
- A DNA sequence encoding the Human APOH protein (P02749) (Ser 263-Cys 345) was expressed with a N-His tag.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product APOH 蛋白
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Apolipoprotein H (Beta-2-Glycoprotein I) (APOH) (AA 20-345) protein (His tag)
APOH 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Apolipoprotein H (Beta-2-Glycoprotein I) (APOH) (AA 20-345) protein (His tag)APOH 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Apolipoprotein H (Beta-2-Glycoprotein I) (APOH) (AA 20-345) protein (His tag)APOH 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Apolipoprotein H (Beta-2-Glycoprotein I) (APOH) (AA 20-345) protein (His tag)APOH 宿主: 人 宿主: Mammalian Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Apolipoprotein H (Beta-2-Glycoprotein I) (APOH) (AA 236-345) protein (GST tag)APOH 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Apolipoprotein H (Beta-2-Glycoprotein I) (APOH) (AA 1-345) protein (GST tag)APOH 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- APOH (Apolipoprotein H (Beta-2-Glycoprotein I) (APOH))
- 别名
- APOH (APOH 产品)
- 别名
- B2G1 Protein, B2GP1 Protein, BG Protein, BETA2 Protein, BHF-1 Protein, MODY6 Protein, NEUROD Protein, bHLHa3 Protein, apoh Protein, APOH Protein, B2GPI Protein, beta-2-GPI Protein, beta2-GPI Protein, LOC100227913 Protein, apolipoprotein H Protein, neuronal differentiation 1 Protein, APOH Protein, NEUROD1 Protein, apoh Protein, Apoh Protein
- 背景
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Abbreviation: APOH
Target Synonym: Beta-2-Glycoprotein 1,APC inhibitor,Apolipoprotein H,Apo-H,Beta-2-Glycoprotein I,B2GPIBeta(2)GPI,APOH,B2G1,B2GP1,BG
Background: Apolipoprotein H (APOH), also known as Beta-2-glycoprotein 1, Activated protein C-binding protein, B2GPI, and B2G1, is a glycoprotein synthesized by liver cells and it is present in the blood associated with plasma lipoproteins. It is an essential cofactor for the binding of certain antiphospholipid antibodies (APA) to anionic phospholipid. APOH binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. APOH may prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells. The activity of APOH appears to involve the binding of agglutenating, negatively charged compounds, and inhibits agglutenation by the contact activation of the intrinsic blood coagulation pathway. APOH causes a reduction of the prothrombinase binding sites on platelets and reduces the activation caused by collagen when thrombin is present at physiological serum concentrations of APOH suggesting a regulatory role of APOH in coagulation. APOH plasma concentrations are strongly associated to metabolic syndrome alterations and vascular disease in type 2 diabetic and could be considered as a clinical marker of cardiovascular risk. APOH is found on several classes of lipoproteins, and is involved in the activation of lipoprotein lipase in lipid metabolism. This single-chain glycoprotein also has been implicated in several physiologic pathways including coagulation and the production of hypertension, which are related to the pathogenesis of primary cerebral hemorrhage (PICH).
- 分子量
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Calculated MW: 9.02 kDa
Observed MW: 12 kDa
- UniProt
- P02749
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