Sclerostin Protein (SOST) (AA 24-213) (His tag)
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- 抗原 See all Sclerostin (SOST) 蛋白
- Sclerostin (SOST)
- 蛋白类型
- Recombinant
- 产品特性
- AA 24-213
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This Sclerostin protein is labelled with His tag.
- 序列
- Gln 24-Tyr 213
- 产品特性
- A DNA sequence encoding the Human SOST protein (Q9BQB4) (Gln24-Tyr213) was expressed with a N-His tag.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product SOST 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- Sclerostin (SOST)
- 别名
- SOST (SOST 产品)
- 别名
- LOC100313724 Protein, CDD Protein, VBCH Protein, 5430411E23Rik Protein, sclerostin Protein, LOC100313724 Protein, SOST Protein, Sost Protein
- 背景
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Abbreviation: SOST
Target Synonym: CDD,DAND6,SOST1,VBCH
Background: Sclerostin, also known as SOST, is a member of the Cerberus/DAN family of BMP antagonists. SOST is asecreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain. It shows sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. SOST is produced by the osteocyte and has anti-anabolic effects on bone formation. It is a negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.
- 分子量
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Calculated MW: 20.79 kDa
Observed MW: 28 kDa
- UniProt
- Q9BQB4
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