FGF23 Protein (AA 24-126) (SUMO Tag,His tag)
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- 抗原 See all FGF23 蛋白
- FGF23 (Fibroblast Growth Factor 23 (FGF23))
- 蛋白类型
- Recombinant
- 产品特性
- AA 24-126
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This FGF23 protein is labelled with SUMO Tag,His tag.
- 序列
- Ala 24-Val 126
- 产品特性
- A DNA sequence encoding the Human FGF23 protein (Q9GZV9) (Ala 24-Val 126) was expressed with a N-SUMO-His tag.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product FGF23 蛋白
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Fibroblast Growth Factor 23 (FGF23) (AA 25-251) (Active) protein (His tag)
FGF23 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） > 90 % AcA, CC Active
Fibroblast Growth Factor 23 (FGF23) (AA 25-251) protein (His tag)FGF23 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Fibroblast Growth Factor 23 (FGF23) (AA 1-251) protein (GST tag)FGF23 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Fibroblast Growth Factor 23 (FGF23) (AA 25-251), (full length) protein (His tag)FGF23 宿主: 大鼠 宿主: 酵母菌 Recombinant > 90 % ELISA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- FGF23 (Fibroblast Growth Factor 23 (FGF23))
- 别名
- FGF23 (FGF23 产品)
- 别名
- FGF23 Protein, ADHR Protein, FGFN Protein, HPDR2 Protein, HYPF Protein, PHPTC Protein, fibroblast growth factor 23 Protein, fgf23 Protein, FGF23 Protein, Fgf23 Protein
- 背景
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Abbreviation: FGF23
Target Synonym: FGF-23,Fgf23,ADHR,FGF23,fibroblast growth factor 23,HPDR2,HYPF,phosphatonin,PHPTC
Background: Fibroblast growth factor 23 (FGF?23) is a 30?32 kDa member of the FGF family, within a subfamily that also includes FGF?19 and FGF?21. FGF proteins contain a 120 amino acid (aa) core FGF domain that exhibits a beta ?trefoil structure. FGF?19 subfamily members are highly diffusible molecules owing to their poor ECM/heparin sulfate binding and plasma?stabilizing intramolecular folds. FGF?23 is produced by osteocytes and osteoblasts in response to high circulating phosphate levels, elevated parathyroid hormone, and circulatory volume loading. It functions as an endocrine phosphatonin by suppressing circulating phosphate levels . FGF?23 interaction with renal proximal tubular epithelium decreases the renal resorption of phosphate by down?regulating phosphate transporters and by suppressing vitamin D production. It also decreases the intestinal absorption of phosphate.
- 分子量
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Calculated MW: 31.22 kDa
Observed MW: 32 kDa
- UniProt
- Q9GZV9
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion
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