VCAM1 Protein (AA 109-318) (GST tag)
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- 抗原 See all VCAM1 蛋白
- VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 109-318
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This VCAM1 protein is labelled with GST tag.
- 序列
- Gln 109-Ser 318
- 产品特性
- A DNA sequence encoding the Human VCAM-1/CD106 protein (P19320) (Gln 109-Ser 318) was expressed with a N-GST tag.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
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- Discover our top product VCAM1 蛋白
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Vascular Cell Adhesion Molecule 1 (VCAM1) (AA 25-697) protein (His tag)
VCAM1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Vascular Cell Adhesion Molecule 1 (VCAM1) protein (Fc Tag)VCAM1 宿主: 小鼠 宿主: 人细胞 Recombinant > 90 % as determined by reducing SDS-PAGE.
Vascular Cell Adhesion Molecule 1 (VCAM1) (AA 25-309) protein (His tag)VCAM1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Vascular Cell Adhesion Molecule 1 (VCAM1) protein (His tag)VCAM1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 80 % by SDS - PAGE SDS
Vascular Cell Adhesion Molecule 1 (VCAM1) (AA 25-123) protein (GST tag)VCAM1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Vascular Cell Adhesion Molecule 1 (VCAM1) (AA 1-739) protein (GST tag)VCAM1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Vascular Cell Adhesion Molecule 1 (VCAM1) (Active) protein (His tag,Fc Tag)VCAM1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
Vascular Cell Adhesion Molecule 1 (VCAM1) (Active) protein (His tag)VCAM1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
Vascular Cell Adhesion Molecule 1 (VCAM1) (AA 25-698) protein (Fc Tag)VCAM1 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
- 别名
- VCAM-1 (VCAM1 产品)
- 别名
- CD106 Protein, INCAM-100 Protein, Vcam-1 Protein, VCAM1B Protein, fi76d06 Protein, wu:fi76d06 Protein, zgc:158875 Protein, VCAM1 Protein, vascular cell adhesion molecule 1 Protein, vascular cell adhesion molecule 1b Protein, VCAM1 Protein, Vcam1 Protein, vcam1b Protein, VCAM-1 Protein
- 背景
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Abbreviation: VCAM-1;CD106
Target Synonym: Vascular Cell Adhesion Protein 1;V-CAM 1;VCAM-1;INCAM-100;CD106;VCAM1;L1CAM
Background: Vascular cell adhesion molecule 1 (VCAM-1), also known as CD106, is a cell surface sialoglycoprotein belonging to the immunoglobulin superfamily. Two forms of VCAM-1 with either six or seven extracellular Ig-like domains are generated by alternative splicing, with the longer form predominant. VCAM-1 is an endothelial ligand for very late antigen-4 (VLA-4) and α4ß7 integrin expressed on leukocytes, and thus mediates leukocyte-endothelial cell adhesion and signal transduction. VCAM-1 expression is induced on endothelial cells during inflammatory bowel disease, atherosclerosis, allograft rejection, infection, and asthmatic responses. During these responses, VCAM-1 forms a scaffold for leukocyte migration. VCAM-1 also activates signals within endothelial cells resulting in the opening of an "endothelial cell gate" through which leukocytes migrate. VCAM-1 has been identified as a potential anti-inflammatory therapeutic target, the hypothesis being that reduced expression of VCAM-1 will slow the development of atherosclerosis. In addition, VCAM-1-activated signals in endothelial cells are regulated by cytokines indicating that it is important to consider both endothelial cell adhesion molecule expression and function during inflammatory processes.
- 分子量
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Calculated MW: 47.99 kDa
Observed MW: 45 kDa
- UniProt
- P19320
- 途径
- Carbohydrate Homeostasis
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