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ESM1 Protein (AA 20-184) (His tag)

ESM1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7505093
发货至: 中国
  • 抗原 See all ESM1 蛋白
    ESM1 (Endothelial Cell-Specific Molecule 1 (ESM1))
    蛋白类型
    Recombinant
    产品特性
    AA 20-184
    宿主
    • 8
    • 7
    • 3
    资源
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This ESM1 protein is labelled with His tag.
    序列
    Trp 20-Arg 184
    产品特性
    A DNA sequence encoding the Human ESM1 protein (Q9NQ30) (Trp 20-Arg 184) was expressed with a N-His tag.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product ESM1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    12 months
  • 抗原
    ESM1 (Endothelial Cell-Specific Molecule 1 (ESM1))
    别名
    ESM1 (ESM1 产品)
    别名
    ESM1 Protein, zgc:153027 Protein, 0610042H23Rik Protein, AV004503 Protein, ESM-1 Protein, Pg25 Protein, endocan Protein, endothelial cell specific molecule 1 Protein, endothelial cell-specific molecule 1 Protein, ESM1 Protein, esm1 Protein, Esm1 Protein
    背景

    Abbreviation: ESM1

    Target Synonym: Endocan,endothelial cell-specific molecule 1,ESM1,ESM-1,IGFBP-rp6

    Background: ESM1 is a secreted protein which is produced by adipocytes. It has been noticed that ESM1 may play some role in obesity-associated vascular disease since circulating ESM-1 levels are reduced in the overweight and obese. ESM1 is mainly expressed in the endothelial cells in human lung and kidney tissues. The expression of ESM1 gene is regulated by cytokines, suggesting that it may play a role in endothelium-dependent pathological disorders. Recently, ESM1 has been described as a specific biomarker of tip cells during neoangiogenesis. Its expression has been shown to be increase in presence of pro-angiogenic growth factors such as VEGF or FGF-2. In hypervascularized cancers, overexpression of endocan has been detected by immunohistochemistry using monoclonal antibodies against ESM1.

    分子量

    Calculated MW: 18.04 kDa

    Observed MW: 25 kDa

    UniProt
    Q9NQ30
    途径
    Growth Factor Binding
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