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MMP7 Protein (AA 95-267) (His tag)

MMP7 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7505088
发货至: 中国
  • 抗原 See all MMP7 蛋白
    MMP7 (Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7))
    蛋白类型
    Recombinant
    产品特性
    AA 95-267
    宿主
    • 9
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    资源
    • 18
    • 2
    • 2
    • 2
    大肠杆菌(E. Coli)
    标记
    This MMP7 protein is labelled with His tag.
    序列
    Tyr 95-Lys 267
    产品特性
    A DNA sequence encoding the Human MMP-7 protein (P09237) (Tyr 95-Lys 267) was expressed with a N-His tag.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product MMP7 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    12 months
  • 抗原
    MMP7 (Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7))
    别名
    MMP-7 (MMP7 产品)
    别名
    MAT Protein, MPMM Protein, MMP-7 Protein, MPSL1 Protein, PUMP-1 Protein, matrilysin Protein, LOC727698 Protein, MMP7 Protein, Matrilysin Protein, matrix metallopeptidase 7 Protein, MMP7 Protein, Mmp7 Protein
    背景

    Abbreviation: MMP-7

    Target Synonym: MMP-7,MPSL1,PUMP-1

    Background: Matrix metalloproteinases (MMPs) are a family of zinc and calcium dependent endopeptidases with the combined ability to degrade all the components of the extracellular matrix. MMP-7 (matrilysin) is expressed in epithelial cells of normal and diseased tissues, and is capable of digesting a large series of proteins of the extracellular matrix including collagen IV and X, gelatin, casein, laminin, aggrecan, entactin, elastin and versican. MMP-7 is implicated in the activation of other proteinases such as plasminogen, MMP-1, MMP-2, and MMP-9. In addition to its roles in connective tissue remodeling and cancer, MMP-7 also regulates intestinal alpha ?defensin activation in innate host defense, releases tumor necrosis factor-alpha in a model of herniated disc resorption, and cleaves FasL to generate a soluble form in a model of prostate involution. Structurally, MMP-7 is the smallest of the MMPs and consists of two domains: a pro-domain that is cleaved upon activation and a catalytic domain containing the zinc-binding site.

    分子量

    Calculated MW: 18.92 kDa

    Observed MW: 20 kDa

    UniProt
    P09237
    途径
    Production of Molecular Mediator of Immune Response
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