MMP7 Protein (AA 95-267) (His tag)
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- 抗原 See all MMP7 蛋白
- MMP7 (Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7))
- 蛋白类型
- Recombinant
- 产品特性
- AA 95-267
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This MMP7 protein is labelled with His tag.
- 序列
- Tyr 95-Lys 267
- 产品特性
- A DNA sequence encoding the Human MMP-7 protein (P09237) (Tyr 95-Lys 267) was expressed with a N-His tag.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product MMP7 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- MMP7 (Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7))
- 别名
- MMP-7 (MMP7 产品)
- 别名
- MAT Protein, MPMM Protein, MMP-7 Protein, MPSL1 Protein, PUMP-1 Protein, matrilysin Protein, LOC727698 Protein, MMP7 Protein, Matrilysin Protein, matrix metallopeptidase 7 Protein, MMP7 Protein, Mmp7 Protein
- 背景
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Abbreviation: MMP-7
Target Synonym: MMP-7,MPSL1,PUMP-1
Background: Matrix metalloproteinases (MMPs) are a family of zinc and calcium dependent endopeptidases with the combined ability to degrade all the components of the extracellular matrix. MMP-7 (matrilysin) is expressed in epithelial cells of normal and diseased tissues, and is capable of digesting a large series of proteins of the extracellular matrix including collagen IV and X, gelatin, casein, laminin, aggrecan, entactin, elastin and versican. MMP-7 is implicated in the activation of other proteinases such as plasminogen, MMP-1, MMP-2, and MMP-9. In addition to its roles in connective tissue remodeling and cancer, MMP-7 also regulates intestinal alpha ?defensin activation in innate host defense, releases tumor necrosis factor-alpha in a model of herniated disc resorption, and cleaves FasL to generate a soluble form in a model of prostate involution. Structurally, MMP-7 is the smallest of the MMPs and consists of two domains: a pro-domain that is cleaved upon activation and a catalytic domain containing the zinc-binding site.
- 分子量
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Calculated MW: 18.92 kDa
Observed MW: 20 kDa
- UniProt
- P09237
- 途径
- Production of Molecular Mediator of Immune Response
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