MASP1 Protein (AA 20-447) (His tag)
-
- 抗原 See all MASP1 蛋白
- MASP1 (Mannan-Binding Lectin Serine Peptidase 1 (MASP1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 20-447
-
宿主
- 人
-
资源
- 大肠杆菌（E. Coli）
- 标记
- This MASP1 protein is labelled with His tag.
- 序列
- His 20-Ala 447
- 产品特性
- A DNA sequence encoding the Human MASP1 protein (P48740) (His20-Ala447) was expressed with a N-His .
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product MASP1 蛋白
-
Mannan-Binding Lectin Serine Peptidase 1 (MASP1) (AA 1-380) protein (GST tag)
MASP1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Mannan-Binding Lectin Serine Peptidase 1 (MASP1) (AA 20-699) protein (His-SUMO Tag)MASP1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 缓冲液
-
Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
-
- 抗原
- MASP1 (Mannan-Binding Lectin Serine Peptidase 1 (MASP1))
- 别名
- MASP1 (MASP1 产品)
- 别名
- AW048060 Protein, CCPII Protein, Crarf Protein, Masp1/3 Protein, 3MC1 Protein, CRARF Protein, CRARF1 Protein, MAP1 Protein, MASP Protein, MASP3 Protein, MAp44 Protein, PRSS5 Protein, RaRF Protein, mannan-binding lectin serine peptidase 1 Protein, mannan binding lectin serine peptidase 1 Protein, Masp1 Protein, MASP1 Protein
- 背景
-
Abbreviation: MASP1
Target Synonym: Mannan-Binding Lectin Serine Protease 1,Complement Factor MASP-3,Mannose-Binding Lectin-Associated Serine Protease 1,MASP-1,RaRF,Serine Protease 5,MASP1,CRARF,CRARF1,PRSS5
Background: Mannan-Binding Lectin Serine Protease 1 (MASP-1) belongs to the peptidase S1 family. MASP1 contains two CUB domains, one EGF-like domain, one peptidase S1 domain and two Sushi (CCP/SCR) domains. MASP1 is primarily expressed in liver. MASP1 involved in the lectin pathway of the complement, performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. MASP1 is synthesized as a zymogen and activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. MASP1 is not directly involved in complement activation but may act as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP2. MASP1 is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. MASP1 is inhibited by SERPING1 and A2M.
- 分子量
-
Calculated MW: 46.97 kDa
Observed MW: 48 kDa
- UniProt
- P48740
- 途径
- Complement System
-
