ROCK2 Protein (AA 904-1140) (His tag)
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- 抗原 See all ROCK2 蛋白
- ROCK2 (rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 904-1140
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This ROCK2 protein is labelled with His tag.
- 序列
- Leu 904-Gly 1140
- 产品特性
- A DNA sequence encoding the Human Rock-2 protein (O75116) (Leu 904-Gly 1140) was expressed with a N-His tag.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product ROCK2 蛋白
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rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2) (AA 1095-1388) protein (His tag)
ROCK2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2) (AA 1279-1388) protein (GST tag)ROCK2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2) protein (Myc-DYKDDDDK Tag)ROCK2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- ROCK2 (rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2))
- 别名
- Rock-2 (ROCK2 产品)
- 别名
- rocka-a Protein, xROK Protein, rock2 Protein, rok2 Protein, ROCK2 Protein, B230113H15Rik Protein, ROKalpha Protein, Rho-kinase Protein, Rock-II Protein, Rock2m Protein, mKIAA0619 Protein, ROCK-II Protein, ROK Protein, Rho-associated, coiled-coil containing protein kinase 2 L homeolog Protein, rho-associated, coiled-coil containing protein kinase 2a Protein, Rho associated coiled-coil containing protein kinase 2 Protein, Rho-associated, coiled-coil containing protein kinase 2 Protein, Rho-associated coiled-coil containing protein kinase 2 Protein, rock2.L Protein, rock2a Protein, ROCK2 Protein, Rock2 Protein
- 背景
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Abbreviation: Rock-2
Target Synonym: Rho kinase 2,Rho-associated,Rho-associated protein kinase 2,ROCK 2,Rock II,Rock2,ROCK2,Rock2m,ROK alpha,ROKalpha
Background: ROCK2/II (Rho-associated protein kinase 2, also Rho-kinase alpha ) is a member of the AGC serine/threonine protein kinase family. ROCK2 is a downstream target of activated RhoA. Its activation results in myosin phosphorylation with subsequent muscle contraction. Human ROCK2 is 1388 amino acids (aa) in length, and appears to be present as a dimer. It contains a protein kinase domain (aa 92?354), a coiled-coil region (aa 429?1131) and a zinc-finger region (aa 1260?1315). Two isoforms show an alternate start site at M686, and a three aa substitution for the N-terminal 444 amino acids.
- 分子量
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Calculated MW: 25.96 kDa
Observed MW: 35 kDa
- UniProt
- O75116
- 途径
- Microtubule Dynamics, WNT signaling, Tube Formation
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