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ADA Protein (AA 11-280) (His tag)

ADA 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7505066
发货至: 中国
  • 抗原 See all ADA 蛋白
    ADA (Adenosine Deaminase (ADA))
    蛋白类型
    Recombinant
    产品特性
    AA 11-280
    宿主
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    资源
    • 12
    • 2
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    • 1
    大肠杆菌(E. Coli)
    标记
    This ADA protein is labelled with His tag.
    序列
    Lys 11-Val 280
    产品特性
    A DNA sequence encoding the Human ADA protein (P00813) (Lys 11-Val 280) was expressed with a N-His tag.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product ADA 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    12 months
  • 抗原
    ADA (Adenosine Deaminase (ADA))
    别名
    ADA (ADA 产品)
    别名
    ADA-like Protein, xada Protein, ADA Protein, CG11994 Protein, Dmel\\CG11994 Protein, DrosADA Protein, dADA Protein, zgc:92028 Protein, adenosine deaminase Protein, adenosine deaminase S homeolog Protein, Adenosine deaminase Protein, ADA Protein, Ada Protein, ada.S Protein, ada Protein
    背景

    Abbreviation: ADA

    Target Synonym: ADA,ADA1,adenine deaminase,Adenosine aminohydrolase,Adenosine Deaminase,EC 3.5.4.4

    Background: Adenosine Deaminase (ADA, adenosine aminohydrolase) is one of the key enzymes of purine nucleotide catabolism. It catalyses the hydrolytic deamination of adenosine and deoxy?adenosine to inosine and deoxyinosine. ADA is expressed in virtually all tissues and is expressed at high levels in T-lymphocytes. Adenosine Deaminase deficiency can cause a form of SCID (severe combined immunodeficiency) and lymphopenia in both B- and T-cell lineages ADA can be used as a sensitive diagnostic marker for tuberculous pleuritis. Although it is primarily a cytosolic enzyme, ADA is known to be a positive regulator of T-cell co?activation due to its binding to CD26 at the cell surface. The interaction of ADA with CD26 regulates lymphocyte-epithelial cell adhesion.

    分子量

    Calculated MW: 29.59 kDa

    Observed MW: 32 kDa

    UniProt
    P00813
    途径
    Regulation of G-Protein Coupled Receptor Protein Signaling, Ribonucleoside Biosynthetic Process
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