PIBF1 Protein (AA 13-203) (His tag)
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- 抗原 See all PIBF1 蛋白
- PIBF1 (Progesterone Immunomodulatory Binding Factor 1 (PIBF1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 13-203
- 宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This PIBF1 protein is labelled with His tag.
- 序列
- Asn 13-Val 203
- 产品特性
- A DNA sequence encoding the Human PIBF protein (Q8WXW3) (Asn 13-Val 203) was expressed with a N-His tag.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product PIBF1 蛋白
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Progesterone Immunomodulatory Binding Factor 1 (PIBF1) (AA 1-757) protein (GST tag)
PIBF1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Progesterone Immunomodulatory Binding Factor 1 (PIBF1) (AA 563-757) protein (His-IF2DI Tag)PIBF1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Progesterone Immunomodulatory Binding Factor 1 (PIBF1) (AA 660-755) protein (GST tag)PIBF1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Progesterone Immunomodulatory Binding Factor 1 (PIBF1) protein (Myc-DYKDDDDK Tag)PIBF1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- PIBF1 (Progesterone Immunomodulatory Binding Factor 1 (PIBF1))
- 别名
- PIBF (PIBF1 产品)
- 别名
- D14Ertd581e Protein, 1700017E21Rik Protein, 4930513H15Rik Protein, 4933438D16Rik Protein, 4933439E17Rik Protein, RGD1305077 Protein, PIBF Protein, C13orf24 Protein, zgc:101063 Protein, MGC80410 Protein, CEP90 Protein, RP11-505F3.1 Protein, progesterone immunomodulatory binding factor 1 Protein, progesterone immunomodulatory binding factor 1 S homeolog Protein, Pibf1 Protein, PIBF1 Protein, pibf1 Protein, pibf1.S Protein
- 背景
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Abbreviation: PIBF
Target Synonym: C13orf24,KIAA1008,PIBF 1,PIBF,PIBF1,PIBF1,Progesterone immunomodulatory binding factor 1,Progesterone induced blocking factor 1
Background: PIBF-1 (Progesterone induced blocking factor 1) is a 90-92 kDa progesterone-inducible molecule initially isolated from the lymphocytes of pregnant women. It is produced by lymphocytes plus villous trophoblast cells, and modulates the activity of cytotoxic NK cells. Human PIBF-1 is 757 amino acids (aa) in length. It contains a possible signal sequence (aa 1-26), two Leu-zippers (aa 311-323 and 643-664), two NLSs (aa 282-285 and 567-573), a bZIP sequence (aa 574-614), and an ER retention motif (aa 752-757). PIBF-1 is found in the nucleus, cytoplasm, and circulation, the result of multiple splice variants. SDS-page shows 90 kDa, 80-83 kDa, 48-52 kDa, 34-35 kDa, and 10-12 kDa isoforms. The 90 kDa form is nuclear and full-length, while the 34-35 kDa form is secreted and likely represents aa 1-223 spliced to aa 683-757. There is a 50-55 kDa form that is apparently intracellular, possibly bioactive and likely represents the N-terminus of the molecule. Over aa 19?419, human PIBF-1 shares 88 % aa identity with mouse PIBF-1.
- 分子量
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Calculated MW: 20.9 kDa
Observed MW: 28 kDa
- UniProt
- Q8WXW3
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