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MCM3 Protein (AA 41-300) (His tag)

MCM3 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7505054
发货至: 中国
  • 抗原 See all MCM3 蛋白
    MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))
    蛋白类型
    Recombinant
    产品特性
    AA 41-300
    宿主
    • 3
    • 1
    资源
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This MCM3 protein is labelled with His tag.
    序列
    Ser 41-Ala 300
    产品特性
    A DNA sequence encoding the Human MCM3 protein (P25205) (Ser 41-Ala 300) was expressed with N-His&C-His tag.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product MCM3 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    12 months
  • 抗原
    MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))
    别名
    MCM3 (MCM3 产品)
    别名
    HCC5 Protein, P1-MCM3 Protein, P1.h Protein, RLFB Protein, AL033361 Protein, C80350 Protein, Mcmd Protein, P1 Protein, p1.m Protein, cb32 Protein, chunp6867 Protein, wu:fa26g03 Protein, CG4206 Protein, DmMCM3 Protein, DmMcm3 Protein, DmeMCM3 Protein, Dmel\\CG4206 Protein, MCM3 Protein, McM3 Protein, Mcp-PCR2 Protein, PCR2 Protein, dMCM3 Protein, xmcm3 Protein, minichromosome maintenance complex component 3 Protein, MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) Protein, Minichromosome maintenance 3 Protein, minichromosome maintenance complex component 3 L homeolog Protein, MCM complex subunit Mcm3 Protein, MCM3 Protein, mcm3 Protein, Mcm3 Protein, mcm3.L Protein
    背景

    Abbreviation: MCM3

    Target Synonym: MCM3,P1 Protein,P1-MCM3,P1.h,p102,P102 protein,MCM 3,mcm3

    Background: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with mCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene.

    分子量

    Calculated MW: 28.49 kDa

    Observed MW: 35 kDa

    UniProt
    P25205
    途径
    DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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