PRKAA1 Protein (AA 421-574) (GST tag)
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- 抗原 See all PRKAA1 蛋白
- PRKAA1 (Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 421-574
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This PRKAA1 protein is labelled with GST tag.
- 序列
- Lys 421-Gln 574
- 产品特性
- A DNA sequence encoding the Human AMPK1 protein (Q13131-2) (Lys 421-Gln 574) was expressed with a N-GST tag.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product PRKAA1 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- PRKAA1 (Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))
- 别名
- AMPK1 (PRKAA1 产品)
- 别名
- AMPK Protein, AMPKa1 Protein, cb116 Protein, im:7154392 Protein, sb:cb130 Protein, wu:fa94c10 Protein, AMPK1 Protein, AMPKalpha1 Protein, AI194361 Protein, AI450832 Protein, AL024255 Protein, C130083N04Rik Protein, ampk Protein, ampka1 Protein, PRKAA1 Protein, protein kinase AMP-activated catalytic subunit alpha 1 Protein, protein kinase, AMP-activated, alpha 1 catalytic subunit Protein, protein kinase, AMP-activated, alpha 1 catalytic subunit L homeolog Protein, PRKAA1 Protein, prkaa1 Protein, Prkaa1 Protein, prkaa1.L Protein
- 背景
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Abbreviation: AMPK1
Target Synonym: PRKAA1,AMPK1,AMPK subunit alpha-1,PRKAA1,ACACA kinase,PRKAA1
Background: AMP-activated protein kinase (AMPK) is a heterotrimeric complex consisting of a catalytic alpha subunit and regulatory beta and gamma subunits. Each subunit exists as alternate isoforms ( alpha 1, alpha 2, beta 1, beta 2, gamma 1, gamma 2, gamma 3), with all 12 combinations able to form complexes. The catalytic alpha subunit of AMPK is activated allosterically by AMP, and by phosphorylation via the AMPK kinases LKB1 and CaMKK beta. AMPK's role in metabolic regulation has implicated this serine/threonine kinase as a therapeutic target in heart disease, obesity, and diabetes.
- 分子量
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Calculated MW: 41.83 kDa
Observed MW: 45 kDa
- UniProt
- Q13131-2
- 途径
- AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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