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Ataxin 2 Protein (ATXN2) (AA 460-600) (GST tag)

ATXN2 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7505038
发货至: 中国
  • 抗原 See all Ataxin 2 (ATXN2) 蛋白
    Ataxin 2 (ATXN2)
    蛋白类型
    Recombinant
    产品特性
    AA 460-600
    宿主
    资源
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This Ataxin 2 protein is labelled with GST tag.
    序列
    Leu 460-Ser 600
    产品特性
    A DNA sequence encoding the Human ATXN2 protein (Q99700) (Leu460-Ser600) was expressed with a N-GST tag.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product ATXN2 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    12 months
  • 抗原
    Ataxin 2 (ATXN2)
    别名
    ATXN2 (ATXN2 产品)
    别名
    ASL13 Protein, ATX2 Protein, SCA2 Protein, TNRC13 Protein, 9630045M23Rik Protein, AW544490 Protein, Sca2 Protein, ATXN2 Protein, MGC115230 Protein, ataxin 2 Protein, ataxin 2 L homeolog Protein, ATXN2 Protein, Atxn2 Protein, atxn2.L Protein
    背景

    Abbreviation: ATXN2

    Target Synonym: Ataxin-2,Spinocerebellar ataxia type 2 protein,Trinucleotide repeat-containing gene 13 protein,ATXN2,ATX2,SCA2,TNRC13

    Background: Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane.Expressed in the brain, heart, liver, skeletal muscle, pancreas and placenta. Isoform 1 is predominant in the brain and spinal cord. Isoform 4 is more abundant in the cerebellum. In the brain, broadly expressed in the amygdala, caudate nucleus, corpus callosum, hippocampus, hypothalamus, substantia nigra, subthalamic nucleus and thalamus.

    分子量

    Calculated MW: 40.4 kDa

    Observed MW: 42 kDa

    UniProt
    Q99700
    途径
    Ribonucleoprotein Complex Subunit Organization
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