Ataxin 2 Protein (ATXN2) (AA 460-600) (GST tag)
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- 抗原 See all Ataxin 2 (ATXN2) 蛋白
- Ataxin 2 (ATXN2)
- 蛋白类型
- Recombinant
- 产品特性
- AA 460-600
- 宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This Ataxin 2 protein is labelled with GST tag.
- 序列
- Leu 460-Ser 600
- 产品特性
- A DNA sequence encoding the Human ATXN2 protein (Q99700) (Leu460-Ser600) was expressed with a N-GST tag.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product ATXN2 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- Ataxin 2 (ATXN2)
- 别名
- ATXN2 (ATXN2 产品)
- 别名
- ASL13 Protein, ATX2 Protein, SCA2 Protein, TNRC13 Protein, 9630045M23Rik Protein, AW544490 Protein, Sca2 Protein, ATXN2 Protein, MGC115230 Protein, ataxin 2 Protein, ataxin 2 L homeolog Protein, ATXN2 Protein, Atxn2 Protein, atxn2.L Protein
- 背景
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Abbreviation: ATXN2
Target Synonym: Ataxin-2,Spinocerebellar ataxia type 2 protein,Trinucleotide repeat-containing gene 13 protein,ATXN2,ATX2,SCA2,TNRC13
Background: Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane.Expressed in the brain, heart, liver, skeletal muscle, pancreas and placenta. Isoform 1 is predominant in the brain and spinal cord. Isoform 4 is more abundant in the cerebellum. In the brain, broadly expressed in the amygdala, caudate nucleus, corpus callosum, hippocampus, hypothalamus, substantia nigra, subthalamic nucleus and thalamus.
- 分子量
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Calculated MW: 40.4 kDa
Observed MW: 42 kDa
- UniProt
- Q99700
- 途径
- Ribonucleoprotein Complex Subunit Organization
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