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NEFM Protein (AA 2-358) (GST tag)

NEFM 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7505037
发货至: 中国
  • 抗原 See all NEFM 蛋白
    NEFM (Neurofilament Triplet M Protein (NEFM))
    蛋白类型
    Recombinant
    产品特性
    AA 2-358
    宿主
    • 3
    • 2
    • 1
    资源
    • 2
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This NEFM protein is labelled with GST tag.
    序列
    Ser 2-Ser 358
    产品特性
    A DNA sequence encoding the Human NEF3 protein (P07197) (Ser2-Ser358) was expressed with a GST.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    12 months
  • 抗原
    NEFM (Neurofilament Triplet M Protein (NEFM))
    别名
    NEF3 (NEFM 产品)
    别名
    NEF3 Protein, NF-M Protein, NFM Protein, Nef3 Protein, Nfm Protein, NF160 Protein, NF165 Protein, nef-m Protein, nef3 Protein, nefm Protein, nf-m Protein, zgc:112359 Protein, nefm-a Protein, nefm-b Protein, neurofilament medium Protein, neurofilament triplet M protein Protein, neurofilament, medium polypeptide Protein, neurofilament medium polypeptide Protein, neurofilament medium L homeolog Protein, neurofilament, medium polypeptide a Protein, neurofilament medium S homeolog Protein, NEFM Protein, Nefm Protein, TVAG_582010 Protein, TVAG_379630 Protein, nefm.L Protein, nefma Protein, nefm.S Protein
    背景

    Abbreviation: NEF3

    Target Synonym: Neurofilament medium polypeptide,NF-M,160 kDa neurofilament protein,Neurofilament 3,Neurofilament triplet M protein,NEFM,NEF3,NFM

    Background: Human NF-M (neurofilament-medium length) is a 145?150 kDa phosphorylated glycoprotein that belongs to the type IV intermediate filament family. It is 915 amino acids in length and contains a 100 amino acid (aa) N-terminal globular region, a 320 aa alpha -helical rod, or central region, and a 500 aa globular tail. The rod region contains a series of heptad repeats that contribute to a coiled-coil interaction with an adjacent NF-M molecule, the first step in intermediate filament oligomerization. The C-terminus shows phosphorylation and O-linked glycosylation. Human NF-M aa 2?358, which includes most of the rod region, shares ~98 % aa sequence identity with corresponding region of mouse, rat and canine NF-M.

    分子量

    Calculated MW: 64.16 kDa

    Observed MW: 60 kDa

    UniProt
    P07197
    途径
    Brown Fat Cell Differentiation
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