THAP1 Protein (AA 1-81) (His tag)
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- 抗原 See all THAP1 蛋白
- THAP1 (THAP Domain Containing, Apoptosis Associated Protein 1 (THAP1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-81
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This THAP1 protein is labelled with His tag.
- 序列
- Met1-Phe81
- 产品特性
- A DNA sequence encoding theHuman THAP1 protein (Q9NVV9) (Met1-Phe81) was expressed with a N-His.
- 纯度
- > 80 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product THAP1 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- THAP1 (THAP Domain Containing, Apoptosis Associated Protein 1 (THAP1))
- 别名
- THAP1 (THAP1 产品)
- 别名
- THAP1 Protein, thap1-a Protein, DYT6 Protein, 4833431A01Rik Protein, AW490810 Protein, zgc:136597 Protein, THAP domain containing, apoptosis associated protein 1 Protein, THAP domain containing 1 Protein, THAP domain containing, apoptosis associated protein 1 L homeolog Protein, thap1 Protein, THAP1 Protein, thap1.L Protein, Thap1 Protein
- 背景
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Abbreviation: THAP1
Target Synonym: THAP domain-containing protein 1
Background: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes, including RRM1. Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. May also have pro-apoptotic activity by potentiating both serum-withdrawal and TNF-induced apoptosis.
- 分子量
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Calculated MW: 9.5 kDa
Observed MW: 11 kDa
- UniProt
- Q9NVV9
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