CDC42 Protein (AA 1-188) (His tag)
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- 抗原 See all CDC42 蛋白
- CDC42 (Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-188
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This CDC42 protein is labelled with His tag.
- 序列
- Met1-Cys188
- 产品特性
- A DNA sequence encoding theHuman CDC42 protein (P60953-2) (Met1-Cys188) was expressed with a N-His.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product CDC42 蛋白
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Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) (AA 1-188) protein (T7 tag)
CDC42 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % by SDS - PAGE SDS
Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) (AA 1-191) protein (GST-pstS1)CDC42 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) (AA 1-191) protein (GST tag)CDC42 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) (AA 94-188) protein (GST tag)CDC42 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)CDC42 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)CDC42 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)CDC42 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- CDC42 (Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42))
- 别名
- CDC42 (CDC42 产品)
- 别名
- CDC42Hs Protein, G25K Protein, AI747189 Protein, AU018915 Protein, cdc42a Protein, wu:fb07d08 Protein, wu:fj62g06 Protein, zgc:63918 Protein, Xcdc42 Protein, cdc42hs Protein, g25k Protein, CDC42 Protein, CG12530 Protein, Cdc42Dm Protein, D-CDC42 Protein, D-Cdc42 Protein, D-cdc42 Protein, DCDC42 Protein, DCdc42 Protein, Dcdc42 Protein, Dm Cdc42 Protein, DmCDC42 Protein, Dmcdc42 Protein, Dmel\\CG12530 Protein, cdc42 Protein, cell division cycle 42 Protein, Cell division control protein 42 homolog Protein, cell division control protein 42 homolog Protein, cell division cycle 42 L homeolog Protein, CG12530 gene product from transcript CG12530-RC Protein, Rho family GTPase Protein, CDC42 Protein, Cdc42 Protein, cdc42 Protein, LOC100636735 Protein, LOC100637699 Protein, LOC100638834 Protein, cdc42.L Protein
- 背景
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Abbreviation: CDC42
Target Synonym: G25K GTP-binding protein
Background: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase.Regulates cell migration.In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections.Required for DOCK10-mediated spine formation in Purkinje cells and hippocampal neurons. In podocytes, facilitates filopodia and podosomes formation upon DOCK11-activation.Upon activation by CaMKII, modulates dendritic spine structural plasticity by relaying CaMKII transient activation to synapse-specific, long-term signaling.Also plays a role in phagocytosis through organization of the F-actin cytoskeleton associated with forming phagocytic cups.
- 分子量
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Calculated MW: 20.9 kDa
Observed MW: 24 kDa
- UniProt
- P60953-2
- 途径
- MAPK Pathway, Microtubule Dynamics, RTK signaling, WNT signaling, TCR Signaling, EGFR Signaling Pathway, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Signaling Events mediated by VEGFR1 and VEGFR2, EGFR Downregulation, VEGF Signaling
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